Literature DB >> 22353221

Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine.

Z-J Huang1, Y Zeng, P Lan, P-H Sun, W-M Chen.   

Abstract

Berberine is an isoquinoline alkaloid isolated from Chinese herbs such as Coptidis Rhizome. This paper is a systematic review of the structural modifications of berberine for different biological activities such as antitumor, antimicrobial, anti-Alzheimer's disease, antihyperglycemic, anti-inflammatory and antimalaria. The current review would provide some useful information for further studies on structural modification of berberine for discovering new drug leads.

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Year:  2011        PMID： 22353221     DOI： 10.2174/138955711797655362

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  12 in total

1.  Berberine Induces Cell Apoptosis through Cytochrome C/Apoptotic Protease-Activating Factor 1/Caspase-3 and Apoptosis Inducing Factor Pathway in Mouse Insulinoma Cells.

Authors:  Xin Fang; Xiao-Liang Miao; Jun-Li Liu; Dong-Wei Zhang; Min Wang; Dan-Dan Zhao; Qian-Qian Mu; Na Yu; Fang-Fang Mo; Hong-Ping Yin; Si-Hua Gao
Journal:  Chin J Integr Med       Date:  2015-07-04       Impact factor: 1.978

2.  Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial Activity and Inhibit Indoleamine Dioxygenase.

Authors:  Esther Jortzik; Kathleen Zocher; Antje Isernhagen; Boniface M Mailu; Stefan Rahlfs; Giampietro Viola; Sergio Wittlin; Nicholas H Hunt; Heiko Ihmels; Katja Becker
Journal:  Antimicrob Agents Chemother       Date:  2015-10-12       Impact factor: 5.191

3.  Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator.

Authors:  Lei Chen; Bo Yu; Yaofang Zhang; Xin Gao; Liang Zhu; Tonghui Ma; Hong Yang
Journal:  PLoS One       Date:  2015-03-06       Impact factor: 3.240

4.  Multiple effects of berberine derivatives on colon cancer cells.

Authors:  Luis Miguel Guamán Ortiz; Micol Tillhon; Michael Parks; Ilaria Dutto; Ennio Prosperi; Monica Savio; Andrea G Arcamone; Franco Buzzetti; Paolo Lombardi; Anna Ivana Scovassi
Journal:  Biomed Res Int       Date:  2014-06-18       Impact factor: 3.411

5.  The effect of berberine on insulin resistance in women with polycystic ovary syndrome: detailed statistical analysis plan (SAP) for a multicenter randomized controlled trial.

Authors:  Ying Zhang; Jin Sun; Yun-Jiao Zhang; Qian-Yun Chai; Kang Zhang; Hong-Li Ma; Xiao-Ke Wu; Jian-Ping Liu
Journal:  Trials       Date:  2016-10-21       Impact factor: 2.279

Review 6.  Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system.

Authors:  Kun Zou; Zhao Li; Yong Zhang; Hao-Yue Zhang; Bo Li; Wei-Liang Zhu; Ji-Ye Shi; Qi Jia; Yi-Ming Li
Journal:  Acta Pharmacol Sin       Date:  2016-12-05       Impact factor: 6.150

7.  Efficacy and Safety of the Traditional Japanese Medicine Keigairengyoto in the Treatment of Acne Vulgaris.

Authors:  Kotaro Ito; Saori Masaki; Manabu Hamada; Tetsuo Tokunaga; Hisashi Kokuba; Kenji Tashiro; Ichiro Yano; Shinichiro Yasumoto; Shinichi Imafuku
Journal:  Dermatol Res Pract       Date:  2018-07-02

Review 8.  Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics.

Authors:  Xiaojun Feng; Antoni Sureda; Samineh Jafari; Zahra Memariani; Devesh Tewari; Giuseppe Annunziata; Luigi Barrea; Sherif T S Hassan; Karel Šmejkal; Milan Malaník; Alice Sychrová; Davide Barreca; Lovro Ziberna; Mohamad Fawzi Mahomoodally; Gokhan Zengin; Suowen Xu; Seyed Mohammad Nabavi; Ai-Zong Shen
Journal:  Theranostics       Date:  2019-03-16       Impact factor: 11.556

9.  Treating type 2 diabetes mellitus with traditional chinese and Indian medicinal herbs.

Authors:  Zhijun Wang; Jeffrey Wang; Patrick Chan
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-07       Impact factor: 2.629

10.  Synthesis and Anticancer Activity of Novel 9-O-Substituted Berberine Derivatives.

Authors:  Viktor Milata; Alexandra Svedova; Zuzana Barbierikova; Eva Holubkova; Ingrid Cipakova; Dana Cholujova; Jana Jakubikova; Miroslav Panik; Sona Jantova; Vlasta Brezova; Lubos Cipak
Journal:  Int J Mol Sci       Date:  2019-05-01       Impact factor: 5.923
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