Nonisotopic in situ hybridization : immunocytochemical detection of specific repetitive sequences on chromosomes and interphase nuclei.

The term in situ hybridization describes a wide range of techniques concerned with the detection of DNA or RNA sequences within individual cells, tissues, or on identifiable regions of chromosomes. The technique utilizes an ability to label DNA or RNA probes so that, following hybridization with complementary sequences in the target tissues, the labeled DNA or RNA can be detected by various techniques.