AIM: To assess the validity of standard liver volume (SLV) calculated using various formulae in the Indian population. METHODS: Data on liver weights of 366 cadavers with no intrinsic liver disease were obtained retrospectively from autopsy records. From these, liver volume (LV) was calculated using the density of formalin-preserved livers, measured prospectively in 15 livers. These volumes were compared with SLV estimated using various formulae. RESULTS: The liver density was found to be 1.162 kg/L. Median (range) age of 366 autopsied cadavers (M:F = 274:92) was 49 [18-70] years. Median (range) body surface area (BSA) and LV was 1.66 (1.25-2.12) square meter and 1,205 (685.3-2102) cc, respectively. There was poor agreement between LV obtained from autopsy data and SLV estimated using formulae derived from the Indians (Indian Model 1: ICC = -0.069, p = 0.655; Indian Model 2: ICC = -0.07015, p = 0.879; Indian Model 3: ICC = -0.06253, p = 0.043), Koreans (ICC = -0.07114, p = <0.0001), Chinese (ICC = -0.0286, p = <0.0001) and Johnson Model (ICC = -0.05764, p = <0.0001). Median difference between the actual LV and SLV as estimated by the Indian Models 1 and 2 are least (29 cc and 6 cc, respectively) and this was followed by Johnson and the Korean Models (149.9 cc and 158.7 cc, respectively). Median difference was the highest with the Indian Model 3 (475.9 cc), followed by Chinese Model (-209.8 cc). CONCLUSIONS: There is poor correlation between the total LV and SLV obtained by various formulae and none are valid in assessing SLV in Indian population.
AIM: To assess the validity of standard liver volume (SLV) calculated using various formulae in the Indian population. METHODS: Data on liver weights of 366 cadavers with no intrinsic liver disease were obtained retrospectively from autopsy records. From these, liver volume (LV) was calculated using the density of formalin-preserved livers, measured prospectively in 15 livers. These volumes were compared with SLV estimated using various formulae. RESULTS: The liver density was found to be 1.162 kg/L. Median (range) age of 366 autopsied cadavers (M:F = 274:92) was 49 [18-70] years. Median (range) body surface area (BSA) and LV was 1.66 (1.25-2.12) square meter and 1,205 (685.3-2102) cc, respectively. There was poor agreement between LV obtained from autopsy data and SLV estimated using formulae derived from the Indians (Indian Model 1: ICC = -0.069, p = 0.655; Indian Model 2: ICC = -0.07015, p = 0.879; Indian Model 3: ICC = -0.06253, p = 0.043), Koreans (ICC = -0.07114, p = <0.0001), Chinese (ICC = -0.0286, p = <0.0001) and Johnson Model (ICC = -0.05764, p = <0.0001). Median difference between the actual LV and SLV as estimated by the Indian Models 1 and 2 are least (29 cc and 6 cc, respectively) and this was followed by Johnson and the Korean Models (149.9 cc and 158.7 cc, respectively). Median difference was the highest with the Indian Model 3 (475.9 cc), followed by Chinese Model (-209.8 cc). CONCLUSIONS: There is poor correlation between the total LV and SLV obtained by various formulae and none are valid in assessing SLV in Indian population.
Authors: See Ching Chan; Chi Leung Liu; Chung Mau Lo; Banny K Lam; Evelyn W Lee; Yik Wong; Sheung Tat Fan Journal: World J Gastroenterol Date: 2006-04-14 Impact factor: 5.742
Authors: Jean-Nicolas Vauthey; Eddie K Abdalla; Dorota A Doherty; Philippe Gertsch; Marc J Fenstermacher; Evelyne M Loyer; Jan Lerut; Roland Materne; Xuemei Wang; Arthur Encarnacion; Delise Herron; Christian Mathey; Giovanni Ferrari; Chuslip Charnsangavej; Kim-Anh Do; Alban Denys Journal: Liver Transpl Date: 2002-03 Impact factor: 5.799
Authors: S Kawasaki; M Makuuchi; H Matsunami; Y Hashikura; T Ikegami; H Chisuwa; T Ikeno; T Noike; T Takayama; H Kawarazaki Journal: Hepatology Date: 1993-11 Impact factor: 17.425
Authors: T Kiuchi; M Kasahara; K Uryuhara; Y Inomata; S Uemoto; K Asonuma; H Egawa; S Fujita; M Hayashi; K Tanaka Journal: Transplantation Date: 1999-01-27 Impact factor: 4.939
Authors: K Kubota; M Makuuchi; K Kusaka; T Kobayashi; K Miki; K Hasegawa; Y Harihara; T Takayama Journal: Hepatology Date: 1997-11 Impact factor: 17.425