Literature DB >> 22349548

Hydroxyethylstarch in cryopreservation - mechanisms, benefits and problems.

A Stolzing1, Y Naaldijk, V Fedorova, S Sethe.   

Abstract

As the progress of regenerative medicine places ever greater attention on cryopreservation of (stem) cells, tried and tested cryopreservation solutions deserve a second look. This article discusses the use of hydroxyethyl starch (HES) as a cryoprotectant. Charting carefully the recorded uses of HES as a cryoprotectant, in parallel to its further clinical use, indicates that some HES subtypes are a useful supplement to dimethysulfoxide (DMSO) in cryopreservation. However, we suggest that the most common admixture ratio of HES and DMSO in cryoprotectant solutions has been established by historical happenstance and requires further investigation and optimization. Copyright Â
© 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22349548     DOI： 10.1016/j.transci.2012.01.007

Source DB:  PubMed          Journal:  Transfus Apher Sci        ISSN： 1473-0502            Impact factor:   1.764


  17 in total

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4.  Handling and Storage Procedures Have Variable Effects on Fatty Acid Content in Fishes with Different Lipid Quantities.

Authors:  Martina D Rudy; Martin J Kainz; Martin Graeve; Stefanie M Colombo; Michael T Arts
Journal:  PLoS One       Date:  2016-08-01       Impact factor: 3.240

5.  Improved Cryopreservation of Human Umbilical Vein Endothelial Cells: A Systematic Approach.

Authors:  A Billal Sultani; Leah A Marquez-Curtis; Janet A W Elliott; Locksley E McGann
Journal:  Sci Rep       Date:  2016-10-06       Impact factor: 4.379

6.  Cryopreservation of dermal fibroblasts and keratinocytes in hydroxyethyl starch-based cryoprotectants.

Authors:  Yahaira Naaldijk; Adiv A Johnson; Annett Friedrich-Stöckigt; Alexandra Stolzing
Journal:  BMC Biotechnol       Date:  2016-12-01       Impact factor: 2.563

7.  Cryopreservation of human cerebral microvascular endothelial cells and astrocytes in suspension and monolayers.

Authors:  Leah A Marquez-Curtis; Reid Bokenfohr; Locksley E McGann; Janet A W Elliott
Journal:  PLoS One       Date:  2021-04-14       Impact factor: 3.240

8.  Effect of different freezing rates during cryopreservation of rat mesenchymal stem cells using combinations of hydroxyethyl starch and dimethylsulfoxide.

Authors:  Yahaira Naaldijk; Marek Staude; Viktoriya Fedorova; Alexandra Stolzing
Journal:  BMC Biotechnol       Date:  2012-08-13       Impact factor: 2.563

9.  A simple and highly effective method for slow-freezing human pluripotent stem cells using dimethyl sulfoxide, hydroxyethyl starch and ethylene glycol.

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Review 10.  Adult multipotent stromal cell cryopreservation: Pluses and pitfalls.

Authors:  Wei Duan; Mandi J Lopez; Kevin Hicok
Journal:  Vet Surg       Date:  2017-10-12       Impact factor: 1.495
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