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Literature DB >> 22349463

Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers.

Fei Li, Yan Feng, Rong Fang, Zhaoyuan Fang, Jufeng Xia, Xiangkun Han, Xin-Yuan Liu, Haiquan Chen, Hongyan Liu, Hongbin Ji.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2012 PMID： 22349463 PMCID： PMC3343653 DOI： 10.1038/cr.2012.27

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

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20 in total

1. Development of thyroid papillary carcinomas secondary to tissue-specific expression of the RET/PTC1 oncogene in transgenic mice.

Authors: M Santoro; G Chiappetta; A Cerrato; D Salvatore; L Zhang; G Manzo; A Picone; G Portella; G Santelli; G Vecchio; A Fusco
Journal: Oncogene Date: 1996-04-18 Impact factor: 9.867

2. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas.

Authors: M Grieco; M Santoro; M T Berlingieri; R M Melillo; R Donghi; I Bongarzone; M A Pierotti; G Della Porta; A Fusco; G Vecchio
Journal: Cell Date: 1990-02-23 Impact factor: 41.582

3. The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line.

Authors: M Santoro; R M Melillo; M Grieco; M T Berlingieri; G Vecchio; A Fusco
Journal: Cell Growth Differ Date: 1993-02

Review 4. Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions.

Authors: William Pao; Vincent A Miller
Journal: J Clin Oncol Date: 2005-03-14 Impact factor: 44.544

5. A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing.

Authors: Young Seok Ju; Won-Chul Lee; Jong-Yeon Shin; Seungbok Lee; Thomas Bleazard; Jae-Kyung Won; Young Tae Kim; Jong-Il Kim; Jin-Hyoung Kang; Jeong-Sun Seo
Journal: Genome Res Date: 2011-12-22 Impact factor: 9.043

Review 6. The GDNF/RET signaling pathway and human diseases.

Authors: M Takahashi
Journal: Cytokine Growth Factor Rev Date: 2001-12 Impact factor: 7.638

7. Never-smokers with lung cancer: epidemiologic evidence of a distinct disease entity.

Authors: Chee-Keong Toh; Fei Gao; Wan-Teck Lim; Swan-Swan Leong; Kam-Weng Fong; Swee-Peng Yap; Anne A L Hsu; Philip Eng; Heng-Nung Koong; Agasthian Thirugnanam; Eng-Huat Tan
Journal: J Clin Oncol Date: 2006-05-20 Impact factor: 44.544

8. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

Authors: J Guillermo Paez; Pasi A Jänne; Jeffrey C Lee; Sean Tracy; Heidi Greulich; Stacey Gabriel; Paula Herman; Frederic J Kaye; Neal Lindeman; Titus J Boggon; Katsuhiko Naoki; Hidefumi Sasaki; Yoshitaka Fujii; Michael J Eck; William R Sellers; Bruce E Johnson; Matthew Meyerson
Journal: Science Date: 2004-04-29 Impact factor: 47.728

9. Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident.

Authors: L Fugazzola; S Pilotti; A Pinchera; T V Vorontsova; P Mondellini; I Bongarzone; A Greco; L Astakhova; M G Butti; E P Demidchik
Journal: Cancer Res Date: 1995-12-01 Impact factor: 12.701

10. Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas.

Authors: S M Jhiang; J E Sagartz; Q Tong; J Parker-Thornburg; C C Capen; J Y Cho; S Xing; C Ledent
Journal: Endocrinology Date: 1996-01 Impact factor: 4.736

32 in total

Review 1. RET fusion gene: translation to personalized lung cancer therapy.

Authors: Takashi Kohno; Koji Tsuta; Katsuya Tsuchihara; Takashi Nakaoku; Kiyotaka Yoh; Koichi Goto
Journal: Cancer Sci Date: 2013-10-01 Impact factor: 6.716

2. Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants.

Authors: Sean T Toenjes; Valeria Garcia; Sean M Maddox; Gregory A Dawson; Maria A Ortiz; F Javier Piedrafita; Jeffrey L Gustafson
Journal: ACS Chem Biol Date: 2019-08-29 Impact factor: 5.100

3. Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

Authors: Oliver Gautschi; Julie Milia; Thomas Filleron; Juergen Wolf; David P Carbone; Dwight Owen; Ross Camidge; Vignhesh Narayanan; Robert C Doebele; Benjamin Besse; Jordi Remon-Masip; Pasi A Janne; Mark M Awad; Nir Peled; Chul-Cho Byoung; Daniel D Karp; Michael Van Den Heuvel; Heather A Wakelee; Joel W Neal; Tony S K Mok; James C H Yang; Sai-Hong Ignatius Ou; Georg Pall; Patrizia Froesch; Gérard Zalcman; David R Gandara; Jonathan W Riess; Vamsidhar Velcheti; Kristin Zeidler; Joachim Diebold; Martin Früh; Sebastian Michels; Isabelle Monnet; Sanjay Popat; Rafael Rosell; Niki Karachaliou; Sacha I Rothschild; Jin-Yuan Shih; Arne Warth; Thomas Muley; Florian Cabillic; Julien Mazières; Alexander Drilon
Journal: J Clin Oncol Date: 2017-03-13 Impact factor: 44.544

Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers.

1. Development of thyroid papillary carcinomas secondary to tissue-specific expression of the RET/PTC1 oncogene in transgenic mice.

2. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas.

3. The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line.

Review 4. Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions.

5. A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing.

Review 6. The GDNF/RET signaling pathway and human diseases.

7. Never-smokers with lung cancer: epidemiologic evidence of a distinct disease entity.

8. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

9. Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident.

10. Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas.

Review 1. RET fusion gene: translation to personalized lung cancer therapy.

2. Leveraging Atropisomerism to Obtain a Selective Inhibitor of RET Kinase with Secondary Activities toward EGFR Mutants.

3. Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

Review 4. Identification of cancer gene fusions based on advanced analysis of the human genome or transcriptome.

5. RET mutations in neuroendocrine tumors: including small-cell lung cancer.

Review 6. RET revisited: expanding the oncogenic portfolio.

Review 7. Values of molecular markers in the differential diagnosis of thyroid abnormalities.

8. Further advances in genetically informed lung cancer medicine.

Review 9. Central role of RET in thyroid cancer.

Review 10. Prognostic and predictive biomarkers in lung cancer. A review.