Literature DB >> 22348525

Asymptomatic splenic infarct and retroperitoneal sepsis in patient with Wegener's granulomatosis.

James C Lee1, Ingra Bringmann, Ahmad Aly.   

Abstract

INTRODUCTION: We present a patient with an unusual combination of surgical findings, complicated by both a medical condition and the treatment there of. PRESENTATION OF CASE: A 52 year-old man with Wegener's granulomatosis presented with groin pain and sepsis while on immunosuppressive therapy. Large retroperitoneal abscesses were found on CT scanning, together with a collapsed left lower lobe of the lung, a complete infarct of the spleen, and evidence of diverticulosis. At the exploratory laparotomy, the infarcted spleen was removed and the retroperitoneal abscesses were drained via a separate lateral incision. Uncomplicated diverticular disease were also confirmed. DISCUSSION: The left lower lobe collapse, infarcted spleen and diverticular disease were all potential sources of the sepsis, but none of them could be clearly linked to the abscesses. The splenic infarct and a post-operative myocardial infarct were likely related to his vasculitic disease.
CONCLUSION: Patients with systemic vasculitis may present with unusual pathologies, and immunosuppressive treatment may also modify clinical presentation. Copyright Â
© 2011 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Year:  2011        PMID: 22348525      PMCID: PMC3282255          DOI: 10.1016/j.ijscr.2011.08.018

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  3 in total

1.  The patient with Wegener's granulomatosis and an intrasplenic mass of unknown origin.

Authors:  S Hafezi-Rachti; R Riess; S Weidner; A Wonka; H D Rupprecht
Journal:  Nephrol Dial Transplant       Date:  2000-06       Impact factor: 5.992

2.  Asymptomatic splenic infarction in Wegener's granulomatosis.

Authors:  D Papaioannides; S N Nikas; M Fotinou; N K Akritidis
Journal:  Ann Rheum Dis       Date:  2002-02       Impact factor: 19.103

Review 3.  Splenic infarction in Wegener's granulomatosis.

Authors:  J Rentsch; G McColl
Journal:  J Rheumatol       Date:  2000-06       Impact factor: 4.666

  3 in total
  2 in total

Review 1.  PR3 vasculitis presenting with symptomatic splenic and renal infarction: a case report and literature review.

Authors:  M J Bottomley; M Gibson; B Alchi
Journal:  BMC Nephrol       Date:  2019-03-06       Impact factor: 2.388

2.  Diffuse Large B Cell Lymphoma Mimicking Granulomatosis with Polyangiitis.

Authors:  Mohammad E Naffaa; Alexander P Rozin; Netanel Horowitz; Ofer Ben-Itzhak; Yolanda Braun-Moscovici; Alexandra Balbir-Gurman
Journal:  Case Rep Rheumatol       Date:  2016-05-18
  2 in total

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