Literature DB >> 22348470

Structural and functional characteristics and properties of metzincins.

N P Balaban1, N L Rudakova, M R Sharipova.   

Abstract

In this review the main families of endopeptidases belonging to the clan of metzincins of zinc-dependent metalloproteinases in organisms of wide evolutional range from bacteria to mammals are considered. The data on classification, physicochemical properties, substrate specificity, and structural features of this group of enzymes are given. The activation mechanisms of metzincins, the role of these proteins in organisms, and their participation in various physiological processes are discussed.

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Year:  2012        PMID： 22348470     DOI： 10.1134/S0006297912020010

Source DB:  PubMed          Journal:  Biochemistry (Mosc)        ISSN： 0006-2979            Impact factor:   2.487


  7 in total

1.  Unraveling the distinctive features of hemorrhagic and non-hemorrhagic snake venom metalloproteinases using molecular simulations.

Authors:  Raoni Almeida de Souza; Natalia Díaz; Ronaldo Alves Pinto Nagem; Rafaela Salgado Ferreira; Dimas Suárez
Journal:  J Comput Aided Mol Des       Date:  2015-12-16       Impact factor: 3.686

Review 2.  Architecture and function of metallopeptidase catalytic domains.

Authors:  Núria Cerdà-Costa; Francesc Xavier Gomis-Rüth
Journal:  Protein Sci       Date:  2014-02       Impact factor: 6.725

3.  A novel mechanism of latency in matrix metalloproteinases.

Authors:  Mar López-Pelegrín; Miroslaw Ksiazek; Abdulkarim Y Karim; Tibisay Guevara; Joan L Arolas; Jan Potempa; F Xavier Gomis-Rüth
Journal:  J Biol Chem       Date:  2015-01-02       Impact factor: 5.157

4.  The evolutionary conservation of the A Disintegrin-like and Metalloproteinase domain with Thrombospondin-1 motif metzincins across vertebrate species and their expression in teleost zebrafish.

Authors:  Frédéric G Brunet; Fiona W Fraser; Marley J Binder; Adam D Smith; Christopher Kintakas; Carolyn M Dancevic; Alister C Ward; Daniel R McCulloch
Journal:  BMC Evol Biol       Date:  2015-02-15       Impact factor: 3.260

5.  Interdomain Contacts and the Stability of Serralysin Protease from Serratia marcescens.

Authors:  Liang Zhang; Anneliese J Morrison; Patrick H Thibodeau
Journal:  PLoS One       Date:  2015-09-17       Impact factor: 3.240

Review 6.  The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression.

Authors:  Ruth M Escalona; Emily Chan; George Kannourakis; Jock K Findlay; Nuzhat Ahmed
Journal:  Int J Mol Sci       Date:  2018-02-02       Impact factor: 5.923

7.  Cloning, expression and characterization of metalloproteinase HypZn from Aspergillus niger.

Authors:  Peng Song; Wei Xu; Kuiming Wang; Yang Zhang; Fei Wang; Xiuling Zhou; Haiying Shi; Wei Feng
Journal:  PLoS One       Date:  2021-11-11       Impact factor: 3.240
  7 in total

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