Literature DB >> 22346336

How patient cost-sharing trends affect adherence and outcomes: a literature review.

Michael T Eaddy, Christopher L Cook, Ken O'Day, Steven P Burch, C Ron Cantrell.   

Abstract

OBJECTIVE: We sought to assess the relationship between patient cost sharing; medication adherence; and clinical, utilization, and economic outcomes.
METHODOLOGY: We conducted a literature review of articles and abstracts published from January 1974 to May 2008. Articles were identified using PubMed, Ovid, medline, Web of Science, and Google Scholar databases. The following terms were used in the search: adherence, compliance, copay, cost sharing, costs, noncompliance, outcomes, hospitalization, utilization, economics, income, and persistence.
RESULTS: We identified and included 160 articles in the review. Although the types of interventions, measures, and populations studied varied widely, we were able to identify relatively clear relationships between cost sharing, adherence, and outcomes. Of the articles that evaluated the relationship between changes in cost sharing and adherence, 85% showed that an increasing patient share of medication costs was significantly associated with a decrease in adherence. For articles that investigated the relationship between adherence and outcomes, the majority noted that increased adherence was associated with a statistically significant improvement in outcomes.
CONCLUSION: Increasing patient cost sharing was associated with declines in medication adherence, which in turn was associated with poorer health outcomes.

Entities:  

Keywords:  adherence; compliance; copays; cost sharing; outcomes

Year:  2012        PMID: 22346336      PMCID: PMC3278192     

Source DB:  PubMed          Journal:  P T        ISSN: 1052-1372


  164 in total

1.  Regular use of inhaled corticosteroids and the long term prevention of hospitalisation for asthma.

Authors:  S Suissa; P Ernst; A Kezouh
Journal:  Thorax       Date:  2002-10       Impact factor: 9.139

2.  Relationship of blood pressure control to adherence with antihypertensive monotherapy in 13 managed care organizations.

Authors:  Thomas J Bramley; Philip P Gerbino; Brian S Nightengale; Feride Frech-Tamas
Journal:  J Manag Care Pharm       Date:  2006-04

3.  Limits on Medicare's ability to control rising spending on cancer drugs.

Authors:  Peter B Bach
Journal:  N Engl J Med       Date:  2009-01-27       Impact factor: 91.245

4.  Adherence to preventive medications: predictors and outcomes in the Diabetes Prevention Program.

Authors:  Elizabeth A Walker; Mark Molitch; M Kaye Kramer; Steven Kahn; Yong Ma; Sharon Edelstein; Kellie Smith; Mariana Kiefer Johnson; Abbas Kitabchi; Jill Crandall
Journal:  Diabetes Care       Date:  2006-09       Impact factor: 19.112

5.  Impact of medication adherence on hospitalization risk and healthcare cost.

Authors:  Michael C Sokol; Kimberly A McGuigan; Robert R Verbrugge; Robert S Epstein
Journal:  Med Care       Date:  2005-06       Impact factor: 2.983

6.  Effectiveness of antihyperlipidemic drug management in clinical practice.

Authors:  S E Andrade; G M Saperia; M L Berger; R Platt
Journal:  Clin Ther       Date:  1999-11       Impact factor: 3.393

7.  Impact of splitting risperidone tablets on medication adherence and on clinical outcomes for patients with schizophrenia.

Authors:  Ellen M Weissman; Cornelia Dellenbaugh
Journal:  Psychiatr Serv       Date:  2007-02       Impact factor: 3.084

8.  Medication adherence and associated hemoglobin A1c in type 2 diabetes.

Authors:  Kimberley Krapek; Kathleen King; Susan S Warren; Karen G George; Dorothy A Caputo; Karen Mihelich; Elizabeth M Holst; Michael B Nichol; Sheng G Shi; Kevin B Livengood; Steve Walden; Teresa J Lubowski
Journal:  Ann Pharmacother       Date:  2004-07-06       Impact factor: 3.154

9.  Compliance with antihypertensive therapy in the elderly: a comparison of fixed-dose combination amlodipine/benazepril versus component-based free-combination therapy.

Authors:  Michael Dickson; Craig A Plauschinat
Journal:  Am J Cardiovasc Drugs       Date:  2008       Impact factor: 3.571

10.  Initiation of statins after hospitalization for coronary heart disease.

Authors:  Xin Ye; Cynthia R Gross; Jon Schommer; Richard Cline; Jianwei Xuan; Wendy L St Peter
Journal:  J Manag Care Pharm       Date:  2007-06
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  80 in total

Review 1.  Does pre-exposure prophylaxis for HIV prevention in men who have sex with men change risk behaviour? A systematic review.

Authors:  Kellie Freeborn; Carmen J Portillo
Journal:  J Clin Nurs       Date:  2018-09       Impact factor: 3.036

2.  High Out-of-Pocket Medical Spending among the Poor and Elderly in Nine Developed Countries.

Authors:  Katherine Baird
Journal:  Health Serv Res       Date:  2016-01-22       Impact factor: 3.402

3.  Health spending among working-age immigrants with disabilities compared to those born in the US.

Authors:  Wassim Tarraf; Elham Mahmoudi; Heather E Dillaway; Hector M González
Journal:  Disabil Health J       Date:  2016-01-29       Impact factor: 2.554

4.  Social Support, Treatment Adherence and Outcome among Hypertensive and Type 2 Diabetes Patients in Ambulatory Care Settings in southwestern Nigeria.

Authors:  Rasaq Adisa; Olamide O Olajide; Titilayo O Fakeye
Journal:  Ghana Med J       Date:  2017-06

5.  Cost-related nonadherence to prescribed medicines among older Canadians in 2014: a cross-sectional analysis of a telephone survey.

Authors:  Augustine Lee; Steve Morgan
Journal:  CMAJ Open       Date:  2017-01-17

6.  Does a Free Office Visit Affect Primary Care-Seeking Behavior? A Study of New Exchange Health Plan Enrollees in Mississippi.

Authors:  Bettina M Beech; Tristan Cordier; Laura E Happe; Laura Trunk; Gilbert S Haugh; Richard Kwong; Vipin Gopal; Roy A Beveridge
Journal:  Am Health Drug Benefits       Date:  2017-04

7.  The Impact of Shortages on Medication Prices: Implications for Shortage Prevention.

Authors:  Michail Alevizakos; Marios Detsis; Christos A Grigoras; Jason T Machan; Eleftherios Mylonakis
Journal:  Drugs       Date:  2016-10       Impact factor: 9.546

8.  Health Insurance and Poverty in Trajectories of Out-of-Pocket Expenditure among Low-Income Middle-Aged Adults.

Authors:  Eunsun Kwon; Sojung Park; Timothy D McBride
Journal:  Health Serv Res       Date:  2018-05-16       Impact factor: 3.402

9.  Investigating the cost implications of including all respiratory medicines in PCRS schemes.

Authors:  Jackie O'Dwyer; Aileen Murphy
Journal:  Ir J Med Sci       Date:  2018-02-01       Impact factor: 1.568

10.  Medication days' supply, adherence, wastage, and cost among chronic patients in Medicaid.

Authors:  Michael Taitel; Leonard Fensterheim; Heather Kirkham; Ryan Sekula; Ian Duncan
Journal:  Medicare Medicaid Res Rev       Date:  2012-09-19
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