Literature DB >> 22344506

Is assisted peritoneal dialysis associated with technique survival when competing events are considered?

Thierry Lobbedez1, Christian Verger, Jean-Philippe Ryckelynck, Emmanuel Fabre, David Evans.   

Abstract

BACKGROUND AND OBJECTIVES: This study assessed whether assisted peritoneal dialysis (PD) was associated with a lower risk for technique failure using methods developed for survival analysis in the presence of competing risks. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This retrospective cohort study, based on data from the French Language Peritoneal Dialysis Registry, analyzed 9822 incident patients starting PD between January 2002 and December 2010. The observation period ended on June 1, 2011. Time to transfer to hemodialysis was compared between patients with assisted PD and those undergoing self-care PD.
RESULTS: There were 5286 patients undergoing assisted PD; 4230 of these were assisted by a community nurse and 1056 by family. Assisted PD patients were older and had a higher Charlson comorbidity index than self-care PD patients. There were 7594 events: 3495 deaths, 2464 transfers to hemodialysis, 1489 renal transplantations, and 146 renal function recoveries. According to a Cox model, assistance and center size were associated with a lower risk for technique failure, whereas hemodialysis before PD, early peritonitis, and transplantation failure were associated with a higher risk for transfer to hemodialysis. A Fine and Gray regression model showed that assisted PD was associated with a lower risk for transfer to hemodialysis.
CONCLUSIONS: Compared with patients undergoing self-care PD, those with assisted PD had a lower risk for transfer to hemodialysis, a higher risk for death, and a lower risk for transplantation.

Entities:  

Mesh:

Year:  2012        PMID: 22344506     DOI: 10.2215/CJN.10161011

Source DB:  PubMed          Journal:  Clin J Am Soc Nephrol        ISSN: 1555-9041            Impact factor:   8.237


  38 in total

Review 1.  Selecting Peritoneal Dialysis in the Older Dialysis Population.

Authors:  Matthew J Oliver; Robert R Quinn
Journal:  Perit Dial Int       Date:  2015-11       Impact factor: 1.756

Review 2.  Peritoneal Dialysis-Related Infection in the Older Population.

Authors:  Cheuk-Chun Szeto
Journal:  Perit Dial Int       Date:  2015-11       Impact factor: 1.756

3.  Are Peritoneal Dialysis Center Characteristics a Modifiable Risk Factor to Improve Peritoneal Dialysis Outcomes?

Authors:  Mark Lambie; Simon J Davies
Journal:  Clin J Am Soc Nephrol       Date:  2017-06-21       Impact factor: 8.237

4.  Translating an understanding of the determinants of technique failure to maximize patient time on peritoneal dialysis?

Authors:  Rajnish Mehrotra
Journal:  Perit Dial Int       Date:  2013 Mar-Apr       Impact factor: 1.756

5.  A Brazilian experience in assisted automated peritoneal dialysis: reliable option or just a palliative therapy?

Authors:  Matthew J Oliver
Journal:  Perit Dial Int       Date:  2013 May-Jun       Impact factor: 1.756

6.  Caregiver burden and hemodialysis.

Authors:  Lewis M Cohen; Michael J Germain
Journal:  Clin J Am Soc Nephrol       Date:  2014-04-10       Impact factor: 8.237

7.  Assisted Peritoneal Dialysis as an Alternative to In-Center Hemodialysis.

Authors:  Edwina A Brown; Martin Wilkie
Journal:  Clin J Am Soc Nephrol       Date:  2016-07-27       Impact factor: 8.237

Review 8.  The Current State of Peritoneal Dialysis.

Authors:  Rajnish Mehrotra; Olivier Devuyst; Simon J Davies; David W Johnson
Journal:  J Am Soc Nephrol       Date:  2016-06-23       Impact factor: 10.121

9.  Timing of Initiation of RRT and Modality Selection.

Authors:  Joanne M Bargman
Journal:  Clin J Am Soc Nephrol       Date:  2015-03-11       Impact factor: 8.237

10.  The impact of transfer from hemodialysis on peritoneal dialysis technique survival.

Authors:  Sharon J Nessim; Joanne M Bargman; S Vanita Jassal; Matthew J Oliver; Yingbo Na; Jeffrey Perl
Journal:  Perit Dial Int       Date:  2013-12-01       Impact factor: 1.756

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