Literature DB >> 22344469

Autologous conjunctival epithelium transplantation and scleral patch graft for postlensectomy wound leakage in Marfan syndrome.

Raffaele Mancino1, Francesco Aiello, Simona Ceccarelli, Cinzia Marchese, Chiara Varesi, Carlo Nucci, Luciano Cerulli.   

Abstract

PURPOSE: We report a case of woman with Marfan syndrome and longstanding postlensectomy scleral wound dehiscence.
METHODS: A 34-year-old woman with Marfan syndrome who underwent lensectomy 20 years ago had conjunctival leakage with chronic hypotony and conjunctival cystic degeneration secondary to scleral wound dehiscence. Presentation, clinical evaluation, and particular treatment with autologous cultivated conjunctival epithelium transplantation and scleral patch graft are described.
RESULTS: A 6-month follow-up confirmed complete epithelization of the ocular surface and absence of leaking from the wound with normal intraocular pressure.
CONCLUSIONS: Transplantation of autologous cultivated conjunctival epithelium appears to be a valid strategy in the treatment of ocular disease requiring extensive excision of the conjunctiva.

Entities:  

Mesh:

Year:  2012        PMID: 22344469     DOI: 10.5301/ejo.5000124

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  5 in total

Review 1.  Multidisciplinary approaches to stimulate wound healing.

Authors:  Rita Businaro; Mariangela Corsi; Tania Di Raimo; Sergio Marasco; Debra L Laskin; Bruno Salvati; Raffaele Capoano; Serafino Ricci; Camilla Siciliano; Giacomo Frati; Elena De Falco
Journal:  Ann N Y Acad Sci       Date:  2016-07-19       Impact factor: 5.691

2.  Delayed sclerotomy wound dehiscence after lensectomy and vitrectomy in Marfan syndrome.

Authors:  Jayanth Sridhar; Jonathan S Chang; Hassan A Aziz; Benjamin P Erickson
Journal:  Oman J Ophthalmol       Date:  2015 Sep-Dec

3.  Long-term follow-up after scleral lens fixation in patients with Marfan syndrome.

Authors:  Jan Luebke; Thomas Reinhard; Hansjuergen Agostini; Daniel Boehringer; Philipp Eberwein
Journal:  BMC Ophthalmol       Date:  2017-12-06       Impact factor: 2.209

4.  Occult Spontaneous Ocular Perforation Presenting as Conjunctival Chemosis in a Patient with Marfan's Syndrome.

Authors:  Nafsika Voulgari; Clarice Giacuzzo; Ann Schalenbourg; George D Kymionis
Journal:  Case Rep Ophthalmol       Date:  2019-10-18

5.  Late onset sclerotomy dehiscence in a patient with Marfan syndrome presenting as recurrent episodes of raised intraocular pressure.

Authors:  Paul Eduard Stanciu; Amy O'Regan; Edel Cosgrave
Journal:  BMJ Case Rep       Date:  2022-08-30
  5 in total

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