| Literature DB >> 22341917 |
Ming-Li Zhao1, En Zhang, Jie Gao, Zhao Zhang, Yu-Tao Zhao, Wen Qu, Hong-Min Liu.
Abstract
A formal synthesis of Jaspine B was completed in 42.4% overall yield with only three purification steps (one by crystallization and two by column chromatography). The key step in the synthesis involves a regio- and stereoselective epoxide ring-opening reaction and the configuration inversion of the C3-hydroxyl group through oxidation and reduction. All of the reagents and materials used were quite common and inexpensive.Entities:
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Year: 2012 PMID： 22341917 DOI： 10.1016/j.carres.2012.01.013
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104