Literature DB >> 22341459

SAMHD1 Joins the red Queen's court.

Vicente Planelles1.   

Abstract

The host restriction factor SAMHD1 hinders lentiviral infection of myeloid cells, a function counteracted by the viral protein Vpx. Two papers in this issue of Cell Host & Microbe document the genetic conflict between SAMHD1 and the Vpr/Vpx proteins, which has subjected SAMHD1 to intense periods of diversifying selection through primate evolution. Copyright Â
© 2012 Elsevier Inc. All rights reserved.

Entities:  

Year:  2012        PMID： 22341459     DOI： 10.1016/j.chom.2012.02.001

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  6 in total

Review 1.  Studies of endogenous retroviruses reveal a continuing evolutionary saga.

Authors:  Jonathan P Stoye
Journal:  Nat Rev Microbiol       Date:  2012-05-08       Impact factor: 60.633

2.  HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.

Authors:  Maria DeLucia; Jennifer Mehrens; Ying Wu; Jinwoo Ahn
Journal:  J Biol Chem       Date:  2013-05-15       Impact factor: 5.157

Review 3.  A cross-species view on viruses.

Authors:  Sara L Sawyer; Nels C Elde
Journal:  Curr Opin Virol       Date:  2012-07-24       Impact factor: 7.090

4.  Kinetic variations between reverse transcriptases of viral protein X coding and noncoding lentiviruses.

Authors:  Gina M Lenzi; Robert A Domaoal; Dong-Hyun Kim; Raymond F Schinazi; Baek Kim
Journal:  Retrovirology       Date:  2014-12-19       Impact factor: 4.602

Review 5.  Molecular mechanisms of HIV immune evasion of the innate immune response in myeloid cells.

Authors:  Mike Mashiba; Kathleen L Collins
Journal:  Viruses       Date:  2012-12-21       Impact factor: 5.048

6.  MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.

Authors:  John L Goodier; Ling E Cheung; Haig H Kazazian
Journal:  PLoS Genet       Date:  2012-10-18       Impact factor: 5.917
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.