Literature DB >> 22340688

Investigation of the mechanical and degradation properties of Mg-Sr and Mg-Zn-Sr alloys for use as potential biodegradable implant materials.

Harpreet S Brar1, Joey Wong, Michele V Manuel.   

Abstract

Magnesium (Mg) has garnered significant interest for its potential use as a biodegradable implant material. Of specific interest in this study is the effect of zinc (Zn) and strontium (Sr) additions on both the mechanical and degradation behaviors in Mg due to their established beneficial effect on strength and microstructural grain refinement while being biocompatible. Three binary Mg-x wt% Sr (x=0.5, 1.0, 1.5) alloys and three ternary Mg-x wt%Zn-0.5 wt% Sr (x=2.0, 4.0, 6.0) were studied to evaluate their mechanical and degradation behavior. Mechanical testing was performed at room temperature on solution-treated and peak aged alloys using microhardness and tensile tests. Degradation was studied using immersion tests in Hanks' solution. Results indicate a decrease in grain size and an increase in strength with increasing Sr and Zn content. When considering degradation behavior Mg-0.5 wt%Sr demonstrated the lowest degradation rate among binary alloys. At constant Sr content at 0.5 wt%, the addition of Zn increased the corrosion rate, with the highest rate for the Mg-6.0 wt%Zn-0.5 wt%Sr. The alloys which best optimized both mechanical and degradation behaviors were Mg-2.0 wt%Zn-0.5 wt%Sr and Mg-4.0 wt%Zn-0.5 wt%Sr. Finally, microstructure and property relationships were evaluated and discussed in reference to each alloy's potential use as a biodegradable implant material. Copyright Â
© 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 22340688     DOI: 10.1016/j.jmbbm.2011.07.018

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  17 in total

1.  Addition of Zn to the ternary Mg-Ca-Sr alloys significantly improves their antibacterial property.

Authors:  Guanping He; Yuanhao Wu; Yu Zhang; Ye Zhu; Yang Liu; Nan Li; Mei Li; Guan Zheng; Baohua He; Qingshui Yin; Yufeng Zheng; Chuanbin Mao
Journal:  J Mater Chem B       Date:  2015-07-27       Impact factor: 6.331

2.  Effects of Sr on the microstructure, mechanical properties and corrosion behavior of Mg-2Zn-xSr alloys.

Authors:  Huiying Lai; Jingyuan Li; Jianxing Li; Yuan Zhang; Yuzhao Xu
Journal:  J Mater Sci Mater Med       Date:  2018-06-12       Impact factor: 3.896

3.  Cytocompatibility and early inflammatory response of human endothelial cells in direct culture with Mg-Zn-Sr alloys.

Authors:  Aaron F Cipriano; Amy Sallee; Myla Tayoba; Mayra C Cortez Alcaraz; Alan Lin; Ren-Guo Guan; Zhan-Yong Zhao; Huinan Liu
Journal:  Acta Biomater       Date:  2016-10-13       Impact factor: 8.947

4.  Degradation of Bioresorbable Mg-4Zn-1Sr Intramedullary Pins and Associated Biological Responses in Vitro and in Vivo.

Authors:  Aaron F Cipriano; Jiajia Lin; Alan Lin; Amy Sallee; Belinda Le; Mayra Celene Cortez Alcaraz; Ren-Guo Guan; Gary Botimer; Serkan Inceoğlu; Huinan Liu
Journal:  ACS Appl Mater Interfaces       Date:  2017-12-14       Impact factor: 9.229

5.  Unique antitumor property of the Mg-Ca-Sr alloys with addition of Zn.

Authors:  Yuanhao Wu; Guanping He; Yu Zhang; Yang Liu; Mei Li; Xiaolan Wang; Nan Li; Kang Li; Guan Zheng; Yufeng Zheng; Qingshui Yin
Journal:  Sci Rep       Date:  2016-02-24       Impact factor: 4.379

6.  Mechanical properties, in vitro corrosion and biocompatibility of newly developed biodegradable Mg-Zr-Sr-Ho alloys for biomedical applications.

Authors:  Yunfei Ding; Jixing Lin; Cuie Wen; Dongmei Zhang; Yuncang Li
Journal:  Sci Rep       Date:  2016-08-24       Impact factor: 4.379

7.  Effect of Hydroxyapatite on the Mechanical Properties and Corrosion Behavior of Mg-Zn-Y Alloy.

Authors:  Chun Chiu; Chih-Te Lu; Shih-Hsun Chen; Keng-Liang Ou
Journal:  Materials (Basel)       Date:  2017-07-26       Impact factor: 3.623

8.  Stimulatory effects of the degradation products from Mg-Ca-Sr alloy on the osteogenesis through regulating ERK signaling pathway.

Authors:  Mei Li; Peng He; Yuanhao Wu; Yu Zhang; Hong Xia; Yufeng Zheng; Yong Han
Journal:  Sci Rep       Date:  2016-09-01       Impact factor: 4.379

9.  Improving in vitro and in vivo corrosion resistance and biocompatibility of Mg-1Zn-1Sn alloys by microalloying with Sr.

Authors:  Yafeng Wen; Qingshan Liu; Jingfeng Wang; Qiming Yang; Weikang Zhao; Bo Qiao; Yuling Li; Dianming Jiang
Journal:  Bioact Mater       Date:  2021-05-19

Review 10.  Biodegradable Magnesium Alloys Developed as Bone Repair Materials: A Review.

Authors:  Chen Liu; Zheng Ren; Yongdong Xu; Song Pang; Xinbing Zhao; Ying Zhao
Journal:  Scanning       Date:  2018-03-13       Impact factor: 1.932

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