Literature DB >> 2233900

Analysis of the sequences flanking the translational start sites of Plasmodium falciparum.

A Saul1, D Battistutta.   

Abstract

The 5' and 3' regions adjacent to the initiation codon in 22 Plasmodium falciparum sequences were examined. A 5' consensus sequence (AAAA/ATG) was found. Although P. falciparum non-translated DNA is A-rich, A occurred significantly more frequently in the 4 positions preceding the initiation ATG than in adjacent non-translated DNA, suggesting that this consensus sequence has functional significance in the initiation of translation. This region has similarities with the equivalent sequences in yeast and Drosophila but differs markedly from that in vertebrates. No significant bias in nucleotide frequencies was found 3' to the initiation codon.

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Year:  1990        PMID： 2233900     DOI： 10.1016/0166-6851(90)90112-y

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  10 in total

1.  Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3.

Authors:  P S Sijwali; B R Shenai; J Gut; A Singh; P J Rosenthal
Journal:  Biochem J       Date:  2001-12-01       Impact factor: 3.857

2.  The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences.

Authors:  J M Vinetz; S K Dave; C A Specht; K A Brameld; B Xu; R Hayward; D A Fidock
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-23       Impact factor: 11.205

3.  Molecular cloning, characterization and localization of PfPK4, an eIF-2alpha kinase-related enzyme from the malarial parasite Plasmodium falciparum.

Authors:  J J Möhrle; Y Zhao; B Wernli; R M Franklin; B Kappes
Journal:  Biochem J       Date:  1997-12-01       Impact factor: 3.857

4.  Proteobacteria-like ferrochelatase in the malaria parasite.

Authors:  Shigeharu Sato; R J M Wilson
Journal:  Curr Genet       Date:  2003-01-18       Impact factor: 3.886

5.  Primary structure of the merozoite surface antigen 1 of Plasmodium vivax reveals sequences conserved between different Plasmodium species.

Authors:  H A del Portillo; S Longacre; E Khouri; P H David
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-01       Impact factor: 11.205

6.  Molecular basis for variable expression of merozoite surface antigen gp45 among American isolates of Babesia bigemina.

Authors:  T G Fisher; T F McElwain; G H Palmer
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

7.  A family of erythrocyte binding proteins of malaria parasites.

Authors:  J H Adams; B K Sim; S A Dolan; X Fang; D C Kaslow; L H Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-01       Impact factor: 11.205

8.  Functional characterization of 5' UTR cis-acting sequence elements that modulate translational efficiency in Plasmodium falciparum and humans.

Authors:  Valentina E Garcia; Rebekah Dial; Joseph L DeRisi
Journal:  Malar J       Date:  2022-01-06       Impact factor: 2.979

9.  Plasmodium vivax merozoite surface protein-3 (PvMSP3): expression of an 11 member multigene family in blood-stage parasites.

Authors:  Jianlin Jiang; John W Barnwell; Esmeralda V S Meyer; Mary R Galinski
Journal:  PLoS One       Date:  2013-05-23       Impact factor: 3.240

10.  Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.

Authors:  S E Francis; I Y Gluzman; A Oksman; A Knickerbocker; R Mueller; M L Bryant; D R Sherman; D G Russell; D E Goldberg
Journal:  EMBO J       Date:  1994-01-15       Impact factor: 11.598
  10 in total

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