| Literature DB >> 2233852 |
R M Evans1, I Watanabe, P A Singer.
Abstract
A muscle biopsy from a patient with hypothyroid myopathy showed striking central changes. "Cores" were seen in most type 1 fibers with oxidative enzyme preparations. Electron microscopy of these areas revealed Z disc streaming, myofilament disruption, and absent mitochondria. The myopathy rapidly improved with thyroxine treatment. This biopsy is of interest, as numerous "cores" have not previously been reported in hypothyroid myopathy.Entities:
Mesh：
Year: 1990 PMID： 2233852 DOI： 10.1002/mus.880131011
Source DB: PubMed Journal: Muscle Nerve ISSN： 0148-639X Impact factor: 3.217