Literature DB >> 22338371

Pathology of tumours originating in the olfactory cleft.

N Boulanger1, R Grosjean, R Jankowski.   

Abstract

UNLABELLED: PROBLEMS/
OBJECTIVE: This study describes the variety of tumours originating in the olfactory cleft which have been treated with endonasal endoscopic surgery.
METHODOLOGY: The study is a retrospective review covering a seven-year period (2004-2010) of the medical records of all patients in whom a tumour originating in the olfactory cleft was excised (72 patients: 63 men and 9 women; age: average of 61 years; range, 19 to 90 years).
RESULTS: The most common tumours in the series were adenocarcinoma (43 [60%] patients), inverted papilloma (7 [10%] patients), respiratory epithelial adematoid hamartoma (6 [8%] patients) and olfactory neuroblastoma (5 [7%] patients).
CONCLUSIONS: The olfactory cleft can be identified as a new surgical field for endonasal endoscopic surgery. This anatomic region is amenable to endoscopic evaluation and the excision of tumours. Exenteration of the olfactory cleft appears to be a key technique for removing adenocarcinoma and can be extended to exenteration of the olfactory groove in cases with intracranial extension. Partial exenteration of the olfactory cleft would seem to be a suitable way of removing benign tumours like inverted papilloma or respiratory epithelial adematoid hamartoma.

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Mesh:

Year:  2011        PMID: 22338371

Source DB:  PubMed          Journal:  B-ENT        ISSN: 1781-782X            Impact factor:   0.082


  1 in total

1.  Olfactory neuroblastoma behavior inside and outside the olfactory cleft.

Authors:  Roger Jankowski; Adrien Russel; Patrice Gallet; Philippe Henrot; Jean Michel Vignaud; Duc Trung Nguyen
Journal:  Surg Radiol Anat       Date:  2014-09-14       Impact factor: 1.246

  1 in total

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