Literature DB >> 22337614

Access to skipped polyene macrolides through ring-closing metathesis: total synthesis of the RNA polymerase inhibitor ripostatin B.

Philipp Winter1, Wolf Hiller, Mathias Christmann.   

Abstract

Rip-Roaring! A convergent total synthesis of antibiotic ripostatin B was developed. A key step in the synthesis is a metathesis reaction allowing for a ring closure to the labile doubly skipped triene macrolide.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2012        PMID： 22337614     DOI： 10.1002/anie.201108692

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  8 in total

1.  Allylic functionalization of unactivated olefins with Grignard reagents.

Authors:  Hongli Bao; Liela Bayeh; Uttam K Tambar
Journal:  Angew Chem Int Ed Engl       Date:  2014-01-23       Impact factor: 15.336

2.  Synthesis and evaluation of novel analogues of ripostatins.

Authors:  Wufeng Tang; Shuang Liu; David Degen; Richard H Ebright; Evgeny V Prusov
Journal:  Chemistry       Date:  2014-08-11       Impact factor: 5.236

3.  Palladium-catalyzed 1,4-difunctionalization of butadiene to form skipped polyenes.

Authors:  Matthew S McCammant; Longyan Liao; Matthew S Sigman
Journal:  J Am Chem Soc       Date:  2013-03-12       Impact factor: 15.419

4.  Development and Investigation of a Site Selective Palladium-Catalyzed 1,4-Difunctionalization of Isoprene using Pyridine-Oxazoline Ligands.

Authors:  Matthew S McCammant; Matthew S Sigman
Journal:  Chem Sci       Date:  2015-02       Impact factor: 9.825

5.  Regio- and Stereoselective Allylindation of Alkynes Using InBr₃ and Allylic Silanes: Synthesis, Characterization, and Application of 1,4-Dienylindiums toward Skipped Dienes.

Authors:  Yoshihiro Nishimoto; Junyi Yi; Tatsuaki Takata; Akio Baba; Makoto Yasuda
Journal:  Molecules       Date:  2018-07-27       Impact factor: 4.411

6.  The Influence of Various N-Heterocyclic Carbene Ligands on Activity of Nitro-Activated Olefin Metathesis Catalysts.

Authors:  Michał Pieczykolan; Justyna Czaban-Jóźwiak; Maura Malinska; Krzysztof Woźniak; Reto Dorta; Anna Rybicka; Anna Kajetanowicz; Karol Grela
Journal:  Molecules       Date:  2020-05-12       Impact factor: 4.411

7.  A reductive coupling strategy towards ripostatin A.

Authors:  Kristin D Schleicher; Timothy F Jamison
Journal:  Beilstein J Org Chem       Date:  2013-07-31       Impact factor: 2.883

8.  Nickel-catalyzed hydroalkylation and hydroalkenylation of 1,3-dienes with hydrazones.

Authors:  Lei Cheng; Ming-Ming Li; Biao Wang; Li-Jun Xiao; Jian-Hua Xie; Qi-Lin Zhou
Journal:  Chem Sci       Date:  2019-09-27       Impact factor: 9.825
  8 in total

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