Literature DB >> 22335186

The Impact of Medicare's lifetime immunosuppression coverage on racial disparities in kidney graft survival.

T F Page1, R S Woodward, D C Brennan.   

Abstract

Beginning January 1, 2000, Medicare effectively extended its coverage of immunosuppression medications from 3 years to lifetime for patients eligible for Medicare on the basis of age or disability status. We examined the impact of this policy on racial disparities in kidney transplant outcomes at 5 years. Using data from the US Renal Data System, we identified cohorts of Medicare-insured kidney transplant recipients according to patient characteristics defining eligibility for lifetime immunosuppression coverage according to the year 2000 policy. We compared racial disparities in graft survival among those eligible for lifetime coverage with the Kaplan-Meier method. We modeled adjusted associations of patient race, patient income, benefits eligibility category and policy exposure with graft loss by multivariable Cox's regression. The racial disparity in graft survival between African American and non-African American among transplant recipients eligible for the lifetime benefit persisted. The graft survival disparity between high- and low-income African American recipients was insignificantly reduced among those eligible for the lifetime benefit. The results of the study suggest that insurance coverage of medication did not eliminate or reduce the racial disparity in graft survival. © Copyright 2012 The American Society of Transplantation and the American Society of Transplant Surgeons.

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Year:  2012        PMID: 22335186     DOI: 10.1111/j.1600-6143.2011.03974.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  4 in total

1.  The association between loss of Medicare, immunosuppressive medication use, and kidney transplant outcomes.

Authors:  Allyson Hart; Sally K Gustafson; Andrew Wey; Nicholas Salkowski; Jon J Snyder; Bertram L Kasiske; Ajay K Israni
Journal:  Am J Transplant       Date:  2019-03-05       Impact factor: 8.086

2.  Racial and ethnic disparities in pediatric renal allograft survival in the United States.

Authors:  Rachel E Patzer; Sumit Mohan; Nancy Kutner; William M McClellan; Sandra Amaral
Journal:  Kidney Int       Date:  2014-10-22       Impact factor: 10.612

3.  Beyond Single Nucleotide Polymorphisms: CYP3A5367 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White Renal Transplant Recipients.

Authors:  Daniel A Brazeau; Kristopher Attwood; Calvin J Meaney; Gregory E Wilding; Joseph D Consiglio; Shirley S Chang; Aijaz Gundroo; Rocco C Venuto; Louise Cooper; Kathleen M Tornatore
Journal:  Front Genet       Date:  2020-08-11       Impact factor: 4.599

4.  Race and sex associations with tacrolimus pharmacokinetics in stable kidney transplant recipients.

Authors:  Kathleen M Tornatore; Calvin J Meaney; Kristopher Attwood; Daniel A Brazeau; Gregory E Wilding; Joseph D Consiglio; Aijaz Gundroo; Shirley S Chang; Vanessa Gray; Louise M Cooper; Rocco C Venuto
Journal:  Pharmacotherapy       Date:  2022-02-01       Impact factor: 6.251

  4 in total

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