Literature DB >> 22334518

Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay.

Timur R Samatov1, Alexander Wolf, Peter Odenwälder, Sergey Bessonov, Céline Deraeve, Robin S Bon, Herbert Waldmann, Reinhard Lührmann.   

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Year:  2012        PMID: 22334518     DOI: 10.1002/cbic.201100790

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  8 in total

Review 1.  Modulating splicing with small molecular inhibitors of the spliceosome.

Authors:  Kerstin A Effenberger; Veronica K Urabe; Melissa S Jurica
Journal:  Wiley Interdiscip Rev RNA       Date:  2016-07-21       Impact factor: 9.957

Review 2.  Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities.

Authors:  Maxime Blijlevens; Jing Li; Victor W van Beusechem
Journal:  Int J Mol Sci       Date:  2021-05-12       Impact factor: 5.923

3.  A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes.

Authors:  Kerstin A Effenberger; Rhonda J Perriman; Walter M Bray; R Scott Lokey; Manuel Ares; Melissa S Jurica
Journal:  J Biomol Screen       Date:  2013-06-14

4.  Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage.

Authors:  Vishal Patil; Josh C Canzoneri; Timur R Samatov; Reinhard Lührmann; Adegboyega K Oyelere
Journal:  RNA       Date:  2012-07-25       Impact factor: 4.942

5.  The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes.

Authors:  Kerstin A Effenberger; Robert C James; Veronica K Urabe; Bailey J Dickey; Roger G Linington; Melissa S Jurica
Journal:  J Biol Chem       Date:  2015-09-25       Impact factor: 5.157

Review 6.  Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy.

Authors:  Maayan Salton; Tom Misteli
Journal:  Trends Mol Med       Date:  2015-12-14       Impact factor: 11.951

7.  Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation.

Authors:  Anzhalika Sidarovich; Cindy L Will; Maria M Anokhina; Javier Ceballos; Sonja Sievers; Dmitry E Agafonov; Timur Samatov; Penghui Bao; Berthold Kastner; Henning Urlaub; Herbert Waldmann; Reinhard Lührmann
Journal:  Elife       Date:  2017-03-16       Impact factor: 8.140

8.  Identification of small molecule inhibitors of pre-mRNA splicing.

Authors:  Andrea Pawellek; Stuart McElroy; Timur Samatov; Lee Mitchell; Andrew Woodland; Ursula Ryder; David Gray; Reinhard Lührmann; Angus I Lamond
Journal:  J Biol Chem       Date:  2014-10-03       Impact factor: 5.157

  8 in total

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