Literature DB >> 22333677

Factors predicting functional and cognitive recovery following severe traumatic, anoxic, and cerebrovascular brain damage.

Nicola Smania1, Renato Avesani, Laura Roncari, Patrizia Ianes, Paolo Girardi, Valentina Varalta, Maria Grazia Gambini, Antonio Fiaschi, Marialuisa Gandolfi.   

Abstract

OBJECTIVES: To compare demographic data, clinical data, and rate of functional and cognitive recovery in patients with severe traumatic, cerebrovascular, or anoxic acquired brain injury (ABI) and to identify factors predicting discharge home. PARTICIPANTS: Three hundred twenty-nine patients with severe ABI (192 with traumatic, 104 with cerebrovascular, and 33 with anoxic brain injury).
DESIGN: Longitudinal prospective study of inpatients attending the intensive Rehabilitation Department of the "Sacro Cuore" Don Calabria Hospital (Negrar, Verona, Italy). MAIN MEASURES: Etiology, sex, age, rehabilitation admission interval, rehabilitation length of stay, discharge destination, Glasgow Coma Scale, Disability Rating Scale (DRS), Glasgow Outcome Scale, Levels of Cognitive Functioning, and Functional Independence Measure.
RESULTS: Predominant etiology was traumatic; male gender was prevalent in all the etiologic groups; patients with traumatic brain injury were younger than the patients in the other groups and had shorter rehabilitation admission interval, greater functional and cognitive outcomes on all considered scales, and a higher frequency of returning home. Patients with anoxic brain injury achieved the lowest grade of functional and cognitive recovery. Age, etiology, and admission DRS score predicted return home.
CONCLUSIONS: Patients with traumatic brain injury achieved greater functional and cognitive improvements than patients with cerebrovascular and anoxic ABI. Age, etiology, and admission DRS score can assist in predicting discharge destination.

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Year:  2013        PMID: 22333677     DOI: 10.1097/HTR.0b013e31823c0127

Source DB:  PubMed          Journal:  J Head Trauma Rehabil        ISSN: 0885-9701            Impact factor:   2.710


  4 in total

1.  Prehospital hypertonic saline resuscitation attenuates the activation and promotes apoptosis of neutrophils in patients with severe traumatic brain injury.

Authors:  Wolfgang G Junger; Shawn G Rhind; Sandro B Rizoli; Joseph Cuschieri; Andrew J Baker; Pang N Shek; David B Hoyt; Eileen M Bulger
Journal:  Shock       Date:  2013-11       Impact factor: 3.454

2.  Prognosis of severe acquired brain injury: Short and long-term outcome determinants and their potential clinical relevance after rehabilitation. A comprehensive approach to analyze cohort studies.

Authors:  Bernardo Lanzillo; Giuseppe Piscosquito; Laura Marcuccio; Anna Lanzillo; Dino Franco Vitale
Journal:  PLoS One       Date:  2019-09-26       Impact factor: 3.240

3.  Functional Independence Measure in Iran: A Confirmatory Factor Analysis and Evaluation of Ceiling and Floor Effects in Traumatic Brain Injury Patients.

Authors:  Sajjad Rezaei; Anoush Dehnadi Moghadam; Naeima Khodadadi; Pardis Rahmatpour
Journal:  Arch Trauma Res       Date:  2015-12-12

4.  Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression.

Authors:  Man-He Zhang; Xiu-Min Zhou; Jian-Zhong Cui; Kai-Jie Wang; Yan Feng; Hong-Ao Zhang
Journal:  Mol Med Rep       Date:  2018-04-19       Impact factor: 2.952

  4 in total

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