Literature DB >> 22332823

Unexpected synthesis of 2,4,5-trisubstituted oxazoles via a tandem aza-Wittig/Michael/isomerization reaction of vinyliminophosphorane.

Hai Xie1, Ding Yuan, Ming-Wu Ding.   

Abstract

2,4,5-Trisubstituted oxazoles 6 were unexpectedly prepared from a tandem reaction of vinyliminophosphorane 3 with various acyl chlorides in a one-pot fashion.

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Year:  2012        PMID： 22332823     DOI： 10.1021/jo202588j

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  Oxazoles for click chemistry II: synthesis of extended heterocyclic scaffolds.

Authors:  Pravin C Patil; Frederick A Luzzio; Donald R Demuth
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

Review 2.  Vinylazides: versatile synthons and magical precursors for the construction of N-heterocycles.

Authors:  Zahra Tashrifi; Mohammad Mohammadi-Khanaposhtani; Bagher Larijani; Halleh Hamedifar; Samira Ansari; Mohammad Mahdavi
Journal:  Mol Divers       Date:  2020-05-30       Impact factor: 2.943

3.  Sequential MCR via Staudinger/Aza-Wittig versus Cycloaddition Reaction to Access Diversely Functionalized 1-Amino-1H-Imidazole-2(3H)-Thiones.

Authors:  Cecilia Ciccolini; Giacomo Mari; Gianfranco Favi; Fabio Mantellini; Lucia De Crescentini; Stefania Santeusanio
Journal:  Molecules       Date:  2019-10-21       Impact factor: 4.411

4.  Facile synthesis of benzothiadiazine 1,1-dioxides, a precursor of RSV inhibitors, by tandem amidation/intramolecular aza-Wittig reaction.

Authors:  Krishna C Majumdar; Sintu Ganai
Journal:  Beilstein J Org Chem       Date:  2013-03-08       Impact factor: 2.883

5.  Investigation on the reactivity of α-azidochalcones with carboxylic acids: Formation of α-amido-1,3-diketones and highly substituted 2-(trifluoromethyl)oxazoles.

Authors:  Kandasamy Rajaguru; Arumugam Mariappan; Rajendran Suresh; Periasamy Manivannan; Shanmugam Muthusubramanian
Journal:  Beilstein J Org Chem       Date:  2015-10-29       Impact factor: 2.883

6.  Access to highly substituted oxazoles by the reaction of α-azidochalcone with potassium thiocyanate.

Authors:  Mysore Bhyrappa Harisha; Pandi Dhanalakshmi; Rajendran Suresh; Raju Ranjith Kumar; Shanmugam Muthusubramanian
Journal:  Beilstein J Org Chem       Date:  2020-08-31       Impact factor: 2.883
  6 in total

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