| Literature DB >> 22332757 |
Steven D Townsend1, Zhongping Tan, Suwei Dong, Shiying Shang, John A Brailsford, Samuel J Danishefsky.
Abstract
Application of native chemical ligation logic to the case of an N-terminal proline is described. Two approaches were studied. One involved incorporation of a 3R-substituted thiyl-proline derivative. Improved results were obtained from a 3R-substituted selenol function, incorporated in the context of an oxidized dimer.Entities:
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Year: 2012 PMID: 22332757 PMCID: PMC3306728 DOI: 10.1021/ja212182q
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419