BACKGROUND: Comorbid depression may play an important role in non-compliance with medical treatment among patients with chronic illnesses. Glaucoma is a potentially blinding chronic disease requiring life-long commitment to medical therapy. Failure to adhere to anti-glaucoma treatment may lead to disease progression and visual loss. OBJECTIVES: To assess the prevalence of depressive symptoms in glaucoma patients and the association between these symptoms and non-compliance with anti-glaucoma therapy. METHODS: In this cross-sectional observational study, compliance with pharmacotherapy was assessed with the Morisky Medication Adherence questionnaire (eight items). Screening for depression was performed by means of the CES-D (Center for Epidemiologic Studies Depression scale). The association between depression and compliance rates was analyzed. RESULTS: The study group comprised 76 glaucoma patients; 19.7% of the subjects were classified as non-compliant (Morisky cutoff 10) and 21.1% suffered from depression (CES-D cutoff > or = 16). We found a similar level of non-compliance when comparing depressed with non-depressed glaucoma patients. However, a correlation was observed between the level of depression and the level of non-compliance (P = 0.04). CONCLUSIONS: Our study revealed a similar rate of depression in glaucoma patients and the general israeli population. The presence of depression was not associated with the presence of non-compliance, yet the level of depression was associated with the level of non-compliance.
BACKGROUND: Comorbid depression may play an important role in non-compliance with medical treatment among patients with chronic illnesses. Glaucoma is a potentially blinding chronic disease requiring life-long commitment to medical therapy. Failure to adhere to anti-glaucoma treatment may lead to disease progression and visual loss. OBJECTIVES: To assess the prevalence of depressive symptoms in glaucomapatients and the association between these symptoms and non-compliance with anti-glaucoma therapy. METHODS: In this cross-sectional observational study, compliance with pharmacotherapy was assessed with the Morisky Medication Adherence questionnaire (eight items). Screening for depression was performed by means of the CES-D (Center for Epidemiologic Studies Depression scale). The association between depression and compliance rates was analyzed. RESULTS: The study group comprised 76 glaucomapatients; 19.7% of the subjects were classified as non-compliant (Morisky cutoff 10) and 21.1% suffered from depression (CES-D cutoff > or = 16). We found a similar level of non-compliance when comparing depressed with non-depressed glaucomapatients. However, a correlation was observed between the level of depression and the level of non-compliance (P = 0.04). CONCLUSIONS: Our study revealed a similar rate of depression in glaucomapatients and the general israeli population. The presence of depression was not associated with the presence of non-compliance, yet the level of depression was associated with the level of non-compliance.
Authors: Scott J Fudemberg; Dilru C Amarasekera; Marlee H Silverstein; Kathryn M Linder; Paul Heffner; Lisa A Hark; Michael Waisbourd Journal: J Community Health Date: 2016-08
Authors: Qi Zhang; Helen Vuong; Xin Huang; YanLing Wang; Nicholas C Brecha; MingLiang Pu; Jie Gao Journal: Sci China Life Sci Date: 2013-06-01 Impact factor: 6.038
Authors: Benjamin E Leiby; Sarah E Hegarty; Tingting Zhan; Jonathan S Myers; L Jay Katz; Julia A Haller; Michael Waisbourd; Christine Burns; Meskerem Divers; Jeanne Molineaux; Jeffrey Henderer; Charles Brodowski; Lisa A Hark Journal: Prev Chronic Dis Date: 2021-05-20 Impact factor: 2.830
Authors: Gabriel Lazcano-Gomez; María de Los Angeles Ramos-Cadena; Margarita Torres-Tamayo; Alejandra Hernandez de Oteyza; Mauricio Turati-Acosta; Jesús Jimenez-Román Journal: Medicine (Baltimore) Date: 2016-11 Impact factor: 1.889