Literature DB >> 22331122

Subretinal fibrosis in Stargardt's disease: case report.

Alexandre Achille Grandinetti1, Ezequiel Portella, Jayme Arana, Natasha Tatiana Vieira Iskorostenski.   

Abstract

The authors describe the clinical characteristics of a 14-year-old female patient with ophthalmoscopic and angiographic aspects of Stargardt's disease in both eyes who developed subretinal fibrosis and localized retinal pigment epithelial hyperplasia in the posterior pole of the right eye 6 months after a mild blunt trauma to the right globe. The left fundus remains with the typical presentation of Stargardt's disease. Our findings support the theory that ocular trauma occurring in patients with Stargardt's disease can precipitate a sequence of events leading to the development of subretinal fibrosis and significant visual loss.

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Year:  2011        PMID: 22331122     DOI: 10.1590/s0004-27492011000600015

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  3 in total

1.  Whole exome sequencing detects homozygosity for ABCA4 p.Arg602Trp missense mutation in a pediatric patient with rapidly progressive retinal dystrophy.

Authors:  Maria Carolina Ortube; Samuel P Strom; Stanley F Nelson; Steven Nusinowitz; Ariadna Martinez; Michael B Gorin
Journal:  BMC Med Genet       Date:  2014-01-20       Impact factor: 2.103

Review 2.  The role of multimodal imaging and vision function testing in ABCA4-related retinopathies and their relevance to future therapeutic interventions.

Authors:  Saoud Al-Khuzaei; Mital Shah; Charlotte R Foster; Jing Yu; Suzanne Broadgate; Stephanie Halford; Susan M Downes
Journal:  Ther Adv Ophthalmol       Date:  2021-12-19

3.  Subretinal Fibrosis in Stargardt's Disease with Fundus Flavimaculatus and ABCA4 Gene Mutation.

Authors:  Settimio Rossi; Francesco Testa; Marcella Attanasio; Ada Orrico; Antonella de Benedictis; Michele Della Corte; Francesca Simonelli
Journal:  Case Rep Ophthalmol       Date:  2012-12-20
  3 in total

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