Andrea Ryan1, Michael O'Keefe. 1. Department of Refractive Surgery, Mater Private Hospital, Dublin, Ireland.
Abstract
PURPOSE: To evaluate the visual outcome and change in higher-order aberrations (HOAs) 1 year post simultaneous wavefront-guided and aspheric photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK). DESIGN: Prospective interventional case series. METHODS: Consecutive myopic patients undergoing PRK (38 eyes of 23 patients) and LASIK (42 eyes of 25 patients) using the Technolas 217z100 excimer laser (Technolas Perfect Vision) in a private laser clinic were included. Main outcome measures were uncorrected distance visual acuity (UDVA), manifest refraction (MRSE), HOAs, and spherical aberration (Z(4)(0)). RESULTS: At 1 year, 87% (32/37) of PRK eyes and 81% (30/37) of LASIK eyes had UDVA of 20/20 or better (P = .75). Mean ± SD MRSE was -0.26 ± 0.31 diopters (D) in the PRK and -0.16 ± 0.34 D in the LASIK group (P = .222). There was no significant increase in total HOA root mean square (RMS) in the PRK group. Mean ± SD total HOA RMS increased from 0.402 ± 0.14 μm to 0.496 ± 0.17 μm (P = .013) in the LASIK group at 1 year. Z(4)(0) increased from mean ± SD -0.045 ± 0.12 μm to -0.109 ± 0.15 μm (P = .006, factor 2.42) in the PRK group and did not significantly increase in the LASIK group (mean ± SD -0.16 ± 0.17 μm to -0.17 ± 0.15 μm (P = .469, factor 1.08) at 6 mm pupil. CONCLUSIONS: Visual outcome was excellent in both treatment groups. HOAs were still increased following LASIK by a factor of 1.23 but not PRK. Z(4)(0) was not induced by LASIK with the treatment algorithm but was negatively induced in PRK eyes.
PURPOSE: To evaluate the visual outcome and change in higher-order aberrations (HOAs) 1 year post simultaneous wavefront-guided and aspheric photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK). DESIGN: Prospective interventional case series. METHODS: Consecutive myopic patients undergoing PRK (38 eyes of 23 patients) and LASIK (42 eyes of 25 patients) using the Technolas 217z100 excimer laser (Technolas Perfect Vision) in a private laser clinic were included. Main outcome measures were uncorrected distance visual acuity (UDVA), manifest refraction (MRSE), HOAs, and spherical aberration (Z(4)(0)). RESULTS: At 1 year, 87% (32/37) of PRK eyes and 81% (30/37) of LASIK eyes had UDVA of 20/20 or better (P = .75). Mean ± SD MRSE was -0.26 ± 0.31 diopters (D) in the PRK and -0.16 ± 0.34 D in the LASIK group (P = .222). There was no significant increase in total HOA root mean square (RMS) in the PRK group. Mean ± SD total HOA RMS increased from 0.402 ± 0.14 μm to 0.496 ± 0.17 μm (P = .013) in the LASIK group at 1 year. Z(4)(0) increased from mean ± SD -0.045 ± 0.12 μm to -0.109 ± 0.15 μm (P = .006, factor 2.42) in the PRK group and did not significantly increase in the LASIK group (mean ± SD -0.16 ± 0.17 μm to -0.17 ± 0.15 μm (P = .469, factor 1.08) at 6 mm pupil. CONCLUSIONS: Visual outcome was excellent in both treatment groups. HOAs were still increased following LASIK by a factor of 1.23 but not PRK. Z(4)(0) was not induced by LASIK with the treatment algorithm but was negatively induced in PRK eyes.