BACKGROUND: Psoriasis is a skin disease with negative physical, psychological and social repercussions for those affected, but we still lack knowledge of how somatic and non-somatic factors directly and indirectly combine to affect patients' quality of life (QoL). OBJECTIVES: This study seeks a better understanding of the relations between symptom severity, discomfort, stigmatization, gender and QoL among psoriasis patients. METHODS: The sample comprised 381 psoriasis patients in inpatient care. Symptom severity and discomfort were measured subjectively with single items. Stigmatization was measured with the Questionnaire on Experience with Skin Complaints. QoL was measured using the Dermatology Life Quality Index (DLQI) and the Short Form-8 Health Survey (SF-8). RESULTS: Symptom severity was associated with higher discomfort, stigmatization and lower skin-related QoL. Symptom severity correlated weakly with more general aspects of QoL as measured by the SF-8. Men and women reported different experiences with discomfort, stigmatization and mental aspects of QoL (SF-8 mental component summary score). Some stigmatization parameters function as mediating variables between symptom severity and QoL. CONCLUSIONS: Our findings suggest that the effect of stigmatization on skin-related QoL is driven by symptom severity and stigmatization combined, whereas its effect on mental health is driven mostly by stigmatization alone. Further, although women and men experience the social impact of psoriasis differently, the effect of stigmatization on QoL is similar for both genders.
BACKGROUND:Psoriasis is a skin disease with negative physical, psychological and social repercussions for those affected, but we still lack knowledge of how somatic and non-somatic factors directly and indirectly combine to affect patients' quality of life (QoL). OBJECTIVES: This study seeks a better understanding of the relations between symptom severity, discomfort, stigmatization, gender and QoL among psoriasispatients. METHODS: The sample comprised 381 psoriasispatients in inpatient care. Symptom severity and discomfort were measured subjectively with single items. Stigmatization was measured with the Questionnaire on Experience with Skin Complaints. QoL was measured using the Dermatology Life Quality Index (DLQI) and the Short Form-8 Health Survey (SF-8). RESULTS: Symptom severity was associated with higher discomfort, stigmatization and lower skin-related QoL. Symptom severity correlated weakly with more general aspects of QoL as measured by the SF-8. Men and women reported different experiences with discomfort, stigmatization and mental aspects of QoL (SF-8 mental component summary score). Some stigmatization parameters function as mediating variables between symptom severity and QoL. CONCLUSIONS: Our findings suggest that the effect of stigmatization on skin-related QoL is driven by symptom severity and stigmatization combined, whereas its effect on mental health is driven mostly by stigmatization alone. Further, although women and men experience the social impact of psoriasis differently, the effect of stigmatization on QoL is similar for both genders.
Authors: K Bangemann; W Schulz; J Wohlleben; A Weyergraf; I Snitjer; T Werfel; G Schmid-Ott; D Böhm Journal: Hautarzt Date: 2014-12 Impact factor: 0.751
Authors: Marloes E van Muijen; S Atalay; L J van Vugt; L M D Vandermaesen; J M P A van den Reek; E M G J de Jong Journal: Drugs Real World Outcomes Date: 2021-03-28
Authors: Carlos Pelayo Hernández-Fernández; Gregorio Carretero; Raquel Rivera; Carlos Ferrándiz; Esteban Daudén; Pablo de Cueva; Isabel Belinchón; Francisco Javier Gómez-García; Enrique Herrera-Acosta; Diana P Ruiz-Genao; Marta Ferrán; Mercé Alsina; Ofelia Baniandrés-Rodríguez; José Luis Sánchez-Carazo; Rafael Botella-Estrada; Antonio Sahuquillo-Torralba; Lourdes Rodríguez; Jaime Vilar-Alejo; Carmen García-Donoso; José M Carrascosa; Mar Llamas-Velasco; Enrique Herrera-Ceballos; Jose Luis López-Estebaranz; Conrad Pujol-Marco; Miguel Angel Descalzo; Ignacio Garcia-Doval Journal: Acta Derm Venereol Date: 2021-01-04 Impact factor: 3.875
Authors: Daniel Pietrzak; Aldona Pietrzak; Ewelina Grywalska; Paweł Kiciński; Jacek Roliński; Helena Donica; Kinga Franciszkiewicz-Pietrzak; Andrzej Borzęcki; Mateusz Socha; Jarosław Niedziałek; Dorota Krasowska Journal: PLoS One Date: 2018-08-09 Impact factor: 3.240