Literature DB >> 22327273

Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands.

Diana C F Monteiro1, Roger M Phillips, Benjamin D Crossley, Jake Fielden, Charlotte E Willans.   

Abstract

A diverse library of cationic silver complexes bearing bis(N-heterocyclic carbene) ligands have been prepared which exhibit cytotoxicity comparable to cisplatin against the adenocarcinomas MCF7 and DLD1. Bidentate ligands show enhanced cytotoxicity over monodentate and macrocyclic ligands.

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Year:  2012        PMID： 22327273     DOI： 10.1039/c2dt12399a

Source DB:  PubMed          Journal:  Dalton Trans        ISSN： 1477-9226            Impact factor:   4.390


  4 in total

1.  Copper (II) complexes with N, S donor pyrazole-based ligands as anticancer agents.

Authors:  Monireh Ghorbanpour; Behzad Soltani; Ali Mota; Jaber Jahanbin Sardroodi; Elnaz Mehdizadeh Aghdam; Ali Shayanfar; Ommoleila Molavi; Rahim Mohammad-Rezaei; Mostafa Ebadi-Nahari; Christopher J Ziegler
Journal:  Biometals       Date:  2022-08-24       Impact factor: 3.378

2.  Polymer encapsulation of anticancer silver-N-heterocyclic carbene complexes.

Authors:  H A Mohamed; M Khuphe; S J Boardman; S Shepherd; R M Phillips; P D Thornton; C E Willans
Journal:  RSC Adv       Date:  2018-03-15       Impact factor: 4.036

3.  Syntheses and Reactivity of New Zwitterionic Imidazolium Trihydridoborate and Triphenylborate Species.

Authors:  Maura Pellei; Riccardo Vallesi; Luca Bagnarelli; H V Rasika Dias; Carlo Santini
Journal:  Molecules       Date:  2020-07-13       Impact factor: 4.411

4.  4-Alkylated Silver-N-Heterocyclic Carbene (NHC) Complexes with Cytotoxic Effects in Leukemia Cells.

Authors:  Alexander H Sandtorv; Calum Leitch; Siv Lise Bedringaas; Bjørn Tore Gjertsen; Hans-René Bjørsvik
Journal:  ChemMedChem       Date:  2015-08-06       Impact factor: 3.466
  4 in total

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