Literature DB >> 22326408

Sensitivity of newer-generation computed tomography scanners for subarachnoid hemorrhage: a Bayesian analysis.

Christopher Gee1, Matthew Dawson, Joseph Bledsoe, Holly Ledyard, Thongphanh Phanthavady, Scott Youngquist, Trever McGuire, Troy Madsen.   

Abstract

BACKGROUND: Subarachnoid hemorrhage (SAH) is a life-threatening condition considered in patients presenting to the emergency department (ED) with acute and severe-onset headache. Currently, the practice pattern for suspected SAH is to perform a non-contrasted computed tomography (CT) scan of the head, followed by lumbar puncture (LP) if the CT is negative. Newer-generation 16-slice CT scanners have been shown in one study to be very sensitive for SAH.
OBJECTIVE: We sought to validate these findings at our institution by retrospectively analyzing the sensitivity of our 16-slice or better CT scanner and performing a bayesian analysis with the results.
METHODS: We utilized ED electronic medical records and the Department of Neurosurgery research database to search for patients admitted from the ED with a diagnosis of SAH from January 1, 2005 to December 31, 2008. We found a total of 134 patients admitted with SAH during this time frame.
RESULTS: Average age was 53.8 years; 62% were female. Presenting complaint was headache in 57%, paresthesia or weakness in 7%, unresponsive in 10%, confusion or altered mental status in 5%, and "other" in 10%. Sensitivity of 16-slice or better CT scanner in our study was 131/134, or 97.8% (95% confidence interval 93.1-99.4%). No patient with a negative CT had a lesion requiring intervention.
CONCLUSION: Our study confirms the high sensitivity of 16-slice or better CT scanners for SAH. This calls into question the need for LP after negative head CT when 16-slice CT or better is used.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22326408     DOI: 10.1016/j.jemermed.2011.09.012

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  7 in total

Review 1.  Spontaneous Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis Describing the Diagnostic Accuracy of History, Physical Examination, Imaging, and Lumbar Puncture With an Exploration of Test Thresholds.

Authors:  Christopher R Carpenter; Adnan M Hussain; Michael J Ward; Gregory J Zipfel; Susan Fowler; Jesse M Pines; Marco L A Sivilotti
Journal:  Acad Emerg Med       Date:  2016-09-06       Impact factor: 3.451

2.  The relationship between abnormal intracranial findings in brain computed tomography and antiplatelet or anticoagulant use in patients with nontraumatic headache: a prospective cohort study.

Authors:  Caner Iskorur; Mustafa Korkut; Secgin Soyuncu
Journal:  Clin Exp Emerg Med       Date:  2022-06-30

3.  Differential diagnostic yield of lumbar puncture in investigation of suspected subarachnoid haemorrhage: a retrospective study.

Authors:  Anna Brunell; Peter Ridefelt; Johan Zelano
Journal:  J Neurol       Date:  2013-01-29       Impact factor: 4.849

Review 4.  Aneurysmal subarachnoid haemorrhage from a neuroimaging perspective.

Authors:  Airton Leonardo de Oliveira Manoel; Ann Mansur; Amanda Murphy; David Turkel-Parrella; Matt Macdonald; R Loch Macdonald; Walter Montanera; Thomas R Marotta; Aditya Bharatha; Khaled Effendi; Tom A Schweizer
Journal:  Crit Care       Date:  2014-11-13       Impact factor: 9.097

5.  Subarachnoid haemorrhage guidelines and clinical practice: a cross-sectional study of emergency department consultants' and neurospecialists' views and risk tolerances.

Authors:  J Lansley; C Selai; A S Krishnan; K Lobotesis; H R Jäger
Journal:  BMJ Open       Date:  2016-09-15       Impact factor: 2.692

6.  The Utility of Lumbar Puncture After a Negative Head CT in the Emergency Department Evaluation of Subarachnoid Hemorrhage.

Authors:  Harman Singh Gill; Evie Grace Marcolini; Douglas Barber; Charles R Wira
Journal:  Yale J Biol Med       Date:  2018-03-28

7.  A common cause of sudden and thunderclap headaches: reversible cerebral vasoconstriction syndrome.

Authors:  Yu-Chen Cheng; Kuei-Hong Kuo; Tzu-Hsien Lai
Journal:  J Headache Pain       Date:  2014-03-01       Impact factor: 7.277

  7 in total

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