Literature DB >> 22326233

How to conduct and interpret ITC experiments accurately for cyclodextrin-guest interactions.

Kawthar Bouchemal1, Silvia Mazzaferro.   

Abstract

Isothermal titration calorimetry (ITC) is one of the most interesting methods for the characterization of the interaction mechanisms of cyclodextrins (CDs) with drugs. In this review we explain how to conduct ITC experiments correctly for CD-guest interactions, how to choose an accurate fitting model for the titration curve and how to interpret carefully the ITC results. Finally, the use of ITC for the characterization of CD-containing nanoparticles is discussed.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22326233     DOI： 10.1016/j.drudis.2012.01.023

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  12 in total

1.  Binding Thermodynamics and Kinetics Calculations Using Chemical Host and Guest: A Comprehensive Picture of Molecular Recognition.

Authors:  Zhiye Tang; Chia-En A Chang
Journal:  J Chem Theory Comput       Date:  2017-12-14       Impact factor: 6.006

2.  Structural Insights into the Host-Guest Complexation between β-Cyclodextrin and Bio-Conjugatable Adamantane Derivatives.

Authors:  Jian-Wei Wang; Ka-Xi Yu; Xin-Yuan Ji; Hongzhen Bai; Wen-Hua Zhang; Xiurong Hu; Guping Tang
Journal:  Molecules       Date:  2021-04-21       Impact factor: 4.411

3.  Synthesis and characterization of a new photoinduced switchable β-cyclodextrin dimer.

Authors:  Florian Hamon; Claire Blaszkiewicz; Marie Buchotte; Estelle Banaszak-Léonard; Hervé Bricout; Sébastien Tilloy; Eric Monflier; Christine Cézard; Laurent Bouteiller; Christophe Len; Florence Djedaini-Pilard
Journal:  Beilstein J Org Chem       Date:  2014-12-04       Impact factor: 2.883

4.  Improving ITC studies of cyclodextrin inclusion compounds by global analysis of conventional and non-conventional experiments.

Authors:  Eléonore Bertaut; David Landy
Journal:  Beilstein J Org Chem       Date:  2014-11-11       Impact factor: 2.883

Review 5.  Carbohydrate-Based Host-Guest Complexation of Hydrophobic Antibiotics for the Enhancement of Antibacterial Activity.

Authors:  Daham Jeong; Sang-Woo Joo; Vijay Vilas Shinde; Eunae Cho; Seunho Jung
Journal:  Molecules       Date:  2017-08-08       Impact factor: 4.411

6.  Inclusion Complexation between α-Cyclodextrin and Oligo(ethylene glycol) Methyl Ether Methacrylate.

Authors:  Marcos Mariano; Oigres Daniel Bernardinelli; Rafael Pires-Oliveira; Guilherme A Ferreira; Watson Loh
Journal:  ACS Omega       Date:  2020-04-17

7.  AtFKBP53: a chimeric histone chaperone with functional nucleoplasmin and PPIase domains.

Authors:  Ajit Kumar Singh; Aritreyee Datta; Chacko Jobichen; Sheng Luan; Dileep Vasudevan
Journal:  Nucleic Acids Res       Date:  2020-02-20       Impact factor: 16.971

8.  Polymer Brush-Grafted Nanoparticles Preferentially Interact with Opsonins and Albumin.

Authors:  Nikolaus Simon Leitner; Martina Schroffenegger; Erik Reimhult
Journal:  ACS Appl Bio Mater       Date:  2020-12-29

9.  Thermodynamic Studies of Interactions between Sertraline Hydrochloride and Randomly Methylated β-Cyclodextrin Molecules Supported by Circular Dichroism Spectroscopy and Molecular Docking Results.

Authors:  Sylwia Belica-Pacha; Mateusz Daśko; Vyacheslav Buko; Ilya Zavodnik; Katarzyna Miłowska; Maria Bryszewska
Journal:  Int J Mol Sci       Date:  2021-11-16       Impact factor: 5.923

10.  Stealth Nanoparticles Grafted with Dense Polymer Brushes Display Adsorption of Serum Protein Investigated by Isothermal Titration Calorimetry.

Authors:  Noga Gal; Martina Schroffenegger; Erik Reimhult
Journal:  J Phys Chem B       Date:  2018-05-18       Impact factor: 2.991
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