| Literature DB >> 22326167 |
Shao-Xing Song1, Ming-Li Wu, Xiao-Peng He, Yu-Bo Zhou, Li Sheng, Jia Li, Guo-Rong Chen.
Abstract
The anomeric mixture of a series of O-galactolipid derivatives is revealed to be more toxic against several cancer cell lines than their either single component with the pure α- or β-configuration. This interesting phenomenon has been confirmed on pairs of synthesized O-galactosyl anomers bearing length-varied alkyl chains at the lipid end. Furthermore, the most potent mixture was determined inoffensive to a normal cell line tested.Entities:
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Year: 2012 PMID: 22326167 DOI: 10.1016/j.bmcl.2012.01.069
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823