Literature DB >> 22325630

Damage in the dorsal striatum alleviates addictive behavior.

J B Muskens1, A F A Schellekens, F E de Leeuw, I Tendolkar, S Hepark.   

Abstract

The ventral striatum has been assigned a major role in addictive behavior. In addition, clinical lesion studies have described involvement of the insula and globus pallidus. To the best of our knowledge, this is the first report of alleviation of alcohol and nicotine addiction after a cerebrovascular incident in the dorsal striatum. The patient was still abstinent from alcohol and nicotine at follow-up. This observation suggests that the dorsal striatum may play a critical role in addiction to alcohol and nicotine.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID： 22325630     DOI： 10.1016/j.genhosppsych.2012.01.008

Source DB:  PubMed          Journal:  Gen Hosp Psychiatry        ISSN： 0163-8343            Impact factor:   3.238


  5 in total

1.  Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats.

Authors:  Atiah H Almalki; Sujan C Das; Fahad S Alshehri; Yusuf S Althobaiti; Youssef Sari
Journal:  Neurosci Lett       Date:  2017-11-22       Impact factor: 3.046

2.  Translational Research on Habit and Alcohol.

Authors:  Theresa H McKim; Tatiana A Shnitko; Donita L Robinson; Charlotte A Boettiger
Journal:  Curr Addict Rep       Date:  2016-02-03

3.  Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain.

Authors:  Mohammed Abul Kashem; Selina Ahmed; Nilufa Sultana; Eakhlas U Ahmed; Russell Pickford; Caroline Rae; Omar Šerý; Iain S McGregor; Vladimir J Balcar
Journal:  Neurochem Res       Date:  2016-01-22       Impact factor: 3.996

4.  Disruption of Cigarette Smoking Addiction After Dorsal Striatum Damage.

Authors:  Chuya Jing; Changxin Jing; Liangcheng Zheng; Ganji Hong; Jingjing Zheng; Lu Yu; Ningning Song; Tengkun Zhang; Qilin Ma; Jie Fang
Journal:  Front Behav Neurosci       Date:  2021-04-01       Impact factor: 3.558

5.  Alterations in brain metabolism and function following administration of low-dose codeine phosphate: 1H-magnetic resonance spectroscopy and resting-state functional magnetic resonance imaging studies.

Authors:  Zhen Cao; Pei-Yin Lin; Zhi-Wei Shen; Ren-Hua Wu; Ye-Yu Xiao
Journal:  Exp Ther Med       Date:  2016-05-18       Impact factor: 2.447
  5 in total

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