| Literature DB >> 22325475 |
Amelia R Mroch1, Jason D Flanagan, Quinn P Stein.
Abstract
We review 3 cases where array comparative genomic hybridization made a difference in the medical management of the patient, ended the diagnostic odyssey, predicted prognosis for the patient, and/or provided closure to the family. Comparative genomic hybridization is a useful tool for testing individuals with clinical examinations suggestive of a genetic syndrome but in which a specific syndrome may be difficult to pinpoint. The cost is similar to that of a standard karyotype but there is a higher yield in children and adults with clinical signs of a genetic syndrome.Entities:
Mesh：
Year: 2012 PMID： 22325475 DOI： 10.1016/j.cppeds.2011.10.003
Source DB: PubMed Journal: Curr Probl Pediatr Adolesc Health Care ISSN： 1538-3199