| Literature DB >> 223198 |
H G Oien, E M Babiarz, D D Soderma, E A Ham, F A Kuehl.
Abstract
A membrane preparation derived from homogenates of the rat kidney has been shown to possess a high affinity for prostaglandins of the E-series. Other prostaglandins including PGI2 had characteristic but significantly weaker binding properties. A 15-hydroxyprostaglandin dehydrogenase (PGDH) was found to be associated with the membrane fraction studied. However it was possible to distinguish between this and the "receptor" binding by kinetic studies and by the use of a new inhibitor highly specific for PGDH.Entities:
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Year: 1979 PMID： 223198 DOI： 10.1016/0090-6980(79)90005-4
Source DB: PubMed Journal: Prostaglandins ISSN： 0090-6980