[The anti-implantation effects of various savine extracts on the pregnant rat].

Ether and ethyl acetate extracts obtained after savin essential oil extraction, were administered, on days 1 to 4, to pregnant rats by intragastric catheter, at doses of 0, 50 or 150 mg/Kg, to search for their possible effects on implantation. The ethyl acetate extract was not toxic. Inversely, the ether extract was responsible for a dose-dependent anti-implantation effect, thus showing that essential oil is not alone responsible for the abortive effect generally attributed to Savin.