Z-M Fang1, X Chen, X Gu, Y Liu, R Zhang, D-R Cao, H-G He. 1. Department of Imaging, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
Abstract
OBJECTIVE: To establish a new magnetic resonance imaging scoring system for diagnosing endolymphatic hydrops. PATIENTS AND METHODS: A total of 214 ears of 107 patients were categorised into five groups: no symptoms, Ménière's disease, sudden deafness, delayed endolymphatic hydrops and other ear disorders. Gadolinium distribution within the labyrinth was scored separately and quantitatively by two radiologists. Multiple independent-sample non-parametric tests, Bayesian discriminant analysis, multivariate logistic regression and receiver operating characteristic curve analyses were performed. RESULTS: The derived scoring model was highly accurate for diagnosing Ménière's disease and delayed endolymphatic hydrops. Two magnetic resonance imaging scoring methods for the perilymphatic space were proposed for the diagnosis of endolymphatic hydrops: a pre-1 value (a new variable that predicts individual probability) of more than 0.3982299, or a sum of all labyrinth component scores of less than 14.5. CONCLUSION: A convenient method is proposed which offers reliable radiological diagnostic criteria for Ménière's disease and delayed endolymphatic hydrops.
OBJECTIVE: To establish a new magnetic resonance imaging scoring system for diagnosing endolymphatic hydrops. PATIENTS AND METHODS: A total of 214 ears of 107 patients were categorised into five groups: no symptoms, Ménière's disease, sudden deafness, delayed endolymphatic hydrops and other ear disorders. Gadolinium distribution within the labyrinth was scored separately and quantitatively by two radiologists. Multiple independent-sample non-parametric tests, Bayesian discriminant analysis, multivariate logistic regression and receiver operating characteristic curve analyses were performed. RESULTS: The derived scoring model was highly accurate for diagnosing Ménière's disease and delayed endolymphatic hydrops. Two magnetic resonance imaging scoring methods for the perilymphatic space were proposed for the diagnosis of endolymphatic hydrops: a pre-1 value (a new variable that predicts individual probability) of more than 0.3982299, or a sum of all labyrinth component scores of less than 14.5. CONCLUSION: A convenient method is proposed which offers reliable radiological diagnostic criteria for Ménière's disease and delayed endolymphatic hydrops.
Authors: Nicholas B Abt; Mohamed Lehar; Carolina Trevino Guajardo; Richard T Penninger; Bryan K Ward; Monica S Pearl; John P Carey Journal: Otol Neurotol Date: 2016-04 Impact factor: 2.311
Authors: Georg Homann; Volker Vieth; Daniel Weiss; Konstantin Nikolaou; Walter Heindel; Mike Notohamiprodjo; Yvonne Böckenfeld Journal: PLoS One Date: 2015-03-13 Impact factor: 3.240