Literature DB >> 22312063

The relevance of the natural history of varicose veins and refunded care.

F Pannier1, E Rabe.   

Abstract

Chronic venous disease (CVD) is one of the most common diseases in our population. Aside from venous symptoms like heaviness and pain, which are present in about 50% of the general population, signs of CVD include varicose veins (VVs), oedema, eczema, venous eczema, hyperpigmentation, white atrophy, lipodermatosclerosis and venous ulcers. The aim of this paper is to review current literature for the relevance of natural history of VVs in refunded care. Available papers on VVs, progression of the disease and complications were reviewed. Prevalence of VVs is high with more than 20% in the general population. Information on progression of uncomplicated VV to chronic venous insufficiency (CVI) is rare. However, most venous ulcers have a primary venous origin. The progression rate of VV to higher clinical stages reaches 4% per year. Among the risk factors are obesity and higher age. Quality of life (QOL) is also reduced in uncomplicated VV in C2 patients. In conclusion, there is evidence from the literature that a high proportion of patients with uncomplicated VVs in the clinical, aetiological, anatomical and pathophysiological classification (CEAP Clinical Class 2) will progress to CVI if untreated. VVs have a negative impact on QOL and clinical symptoms. VV patients with CVI (C3-C6) as well as those C2 patients with severe clinical symptoms and impaired QOL due to CVD should be treated with ablation of the VVs in a refunded care system.

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Year:  2012        PMID: 22312063     DOI: 10.1258/phleb.2012.012s23

Source DB:  PubMed          Journal:  Phlebology        ISSN: 0268-3555            Impact factor:   1.740


  8 in total

1.  Melatonin alleviates inflammation-induced apoptosis in human umbilical vein endothelial cells via suppression of Ca2+-XO-ROS-Drp1-mitochondrial fission axis by activation of AMPK/SERCA2a pathway.

Authors:  Jiasen Cui; Zeng Li; Shunjiu Zhuang; Shaohong Qi; Li Li; Junwen Zhou; Wan Zhang; Yun Zhao
Journal:  Cell Stress Chaperones       Date:  2017-09-09       Impact factor: 3.667

Review 2.  S2k guidelines: diagnosis and treatment of varicose veins.

Authors:  F Pannier; T Noppeney; J Alm; F X Breu; G Bruning; I Flessenkämper; H Gerlach; K Hartmann; B Kahle; H Kluess; E Mendoza; D Mühlberger; A Mumme; H Nüllen; K Rass; S Reich-Schupke; D Stenger; M Stücker; C G Schmedt; T Schwarz; J Tesmann; J Teßarek; S Werth; E Valesky
Journal:  Hautarzt       Date:  2022-04-19       Impact factor: 1.198

3.  Symptoms in patients with skin changes due to chronic venous insufficiency often lead to emergency care service: an Italian observational study.

Authors:  Michele Ruggiero; Raffaele Grande; Agostino Naso; Lucia Butrico; Paolo Rubino; Girolamo Domenico Placida; Marco Cannistrà; Raffaele Serra
Journal:  Int Wound J       Date:  2015-09-08       Impact factor: 3.315

4.  Morphology and Progression in Primary Varicose Vein Disorder Due to 677C>T and 1298A>C Variants of MTHFR.

Authors:  Christoph Wilmanns; Alexis Cooper; Leesa Wockner; Sotirios Katsandris; Nadine Glaser; Alexander Meyer; Oliver Bartsch; Harald Binder; Paul Karl Walter; Ulrich Zechner
Journal:  EBioMedicine       Date:  2015-01-15       Impact factor: 8.143

Review 5.  Pathophysiological Mechanisms of Chronic Venous Disease and Implications for Venoactive Drug Therapy.

Authors:  Armando Mansilha; Joel Sousa
Journal:  Int J Mol Sci       Date:  2018-06-05       Impact factor: 5.923

6.  Burden and Suffering in Chronic Venous Disease.

Authors:  Andrew N Nicolaides; Nicos Labropoulos
Journal:  Adv Ther       Date:  2019-02-13       Impact factor: 3.845

Review 7.  The Seriousness of Chronic Venous Disease: A Review of Real-World Evidence.

Authors:  Alun H Davies
Journal:  Adv Ther       Date:  2019-02-13       Impact factor: 3.845

8.  Patient and clinician experiences and opinions of the use of a novel home use medical device in the treatment of peripheral vascular disease - a qualitative study.

Authors:  Charlotte E Sedgwick; Charlotte Growcott; Shehnaz Akhtar; Daniel Parker; Erik Mulder Pettersen; Farina Hashmi; Anita Ellen Williams
Journal:  J Foot Ankle Res       Date:  2021-12-03       Impact factor: 2.303

  8 in total

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