Literature DB >> 22311215

Metabolic syndrome and dementia associated with Parkinson's disease: impact of age and hypertension.

Arthur Oscar Schelp1, Cristiane Lara Mendes-Chiloff, Rodrigo Bazan, Vanessa Cristina Paduan, Ana Beatriz Maringolo Pioltini.   

Abstract

OBJECTIVE: To determine correlations between age and metabolic disorders in Parkinson's disease (PD) patients.
METHODS: This observational cross-sectional study included brief tests for dementia and the Mattis test. Signals of metabolic syndrome were evaluated.
RESULTS: There was no significant effect from the presence of hypertension (OR=2.36 for patients under 65 years old and OR=0.64 for patients over 65), diabetes or hypercholesterolemia regarding occurrences of dementia associated with PD (24% of the patients). The study demonstrated that each year of age increased the estimated risk of dementia in PD patients by 9% (OR=1.09; 95%CI: 1.01-1.17).
CONCLUSION: There was no evidence to correlate the presence of metabolic syndrome with the risk of dementia that was associated with PD. The study confirmed that dementia in PD is age dependent and not related to disease duration.

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Year:  2012        PMID: 22311215     DOI: 10.1590/s0004-282x2012000200008

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  1 in total

1.  Reduced vascular risk factors in Parkinson's disease dementia and dementia with Lewy bodies compared to Alzheimer's disease.

Authors:  Po-Chi Chan; Cheng-Yu Wei; Guang-Uei Hung; Pai-Yi Chiu
Journal:  Brain Behav       Date:  2018-02-05       Impact factor: 2.708

  1 in total

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