Literature DB >> 22310749

Blood transfusions in radical prostatectomy: a contemporary population-based analysis.

Jan Schmitges1, Maxine Sun, Firas Abdollah, Quoc-Dien Trinh, Claudio Jeldres, Lars Budäus, Marco Bianchi, Jens Hansen, Thorsten Schlomm, Paul Perrotte, Markus Graefen, Pierre I Karakiewicz.   

Abstract

OBJECTIVE: To examine the homologous blood transfusion (HBT), autologous blood transfusion (ABT) and intraoperative blood conservation technique (IOBCT) rates and trends at open (ORP) and minimally invasive radical prostatectomy (MIRP).
METHODS: The Nationwide Inpatient Sample was queried. Multivariable logistic regression models focused on all three transfusion types. Covariables consisted of procedure specific annual hospital caseload (AHC), year of surgery, age, Charlson Comorbidity Index, and region.
RESULTS: Overall, 119,966 patients underwent radical prostatectomy between 1998 and 2007. The HBT, ABT, and IOBCT rates were 6.2%, 6.0%, and 1.2%, respectively. HBT rates ranged from 5.1-5.1% between 1998 and 2007 (P=.49) vs 9.4-2.7% (P<.001) for ABT vs 1.9-0.9% (P=.003) for IOBCT in the same time period, respectively. In multivariable analyses, ORP patients treated at intermediate (odds ratio [OR] 1.48, P=.003) and low (OR 2.73, P<.001) AHC institutions were more likely to receive an HBT than ORP patients treated at high AHC institutions. Conversely, MIRP patients treated at high (OR 0.46, P=.040), intermediate (OR 0.27, P=.001), and low (OR 0.59, P=.015) AHC institutions were less likely to receive an HBT than ORP patients treated at high AHC institutions.
CONCLUSION: Our results indicate that the overall transfusion rate at radical prostatectomy decreased within the last decade because of a substantial decline in ABT use. Moreover, MIRP protects from HBT, even when performed at low AHC Centers.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22310749     DOI: 10.1016/j.urology.2011.08.079

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  5 in total

1.  Factors associated with red blood cell, platelet, and plasma transfusions among inpatient hospitalizations: a nationally representative study in the United States.

Authors:  Ruchika Goel; Eshan U Patel; Jodie L White; Meera R Chappidi; Paul M Ness; Melissa M Cushing; Clifford M Takemoto; Beth H Shaz; Steven M Frank; Aaron A R Tobian
Journal:  Transfusion       Date:  2018-12-12       Impact factor: 3.157

Review 2.  Comparative effectiveness of robotic and open radical prostatectomy.

Authors:  Rodrigo Rodrigues Pessoa; Paul Maroni; Janet Kukreja; Simon P Kim
Journal:  Transl Androl Urol       Date:  2021-05

3.  The impact of intra-operative cell salvage during open radical prostatectomy.

Authors:  Ned Kinnear; Bridget Heijkoop; Lina Hua; Derek B Hennessey; Daniel Spernat
Journal:  Transl Androl Urol       Date:  2018-05

4.  Safety, efficacy and cost of intra-operative cell salvage during open radical prostatectomy.

Authors:  Jennifer Xu; Ned Kinnear; Lydia Johns Putra
Journal:  Transl Androl Urol       Date:  2021-03

5.  Medical Travel among Non-Seoul Residents to Seek Prostate Cancer Treatment in Medical Facilities of Seoul.

Authors:  Jae Heon Kim; So Young Kim; Seok-Joong Yun; Jae Il Chung; Hoon Choi; Ho Song Yu; Yun-Sok Ha; In-Chang Cho; Hyung Joon Kim; Hyun Chul Chung; Jun Sung Koh; Wun-Jae Kim; Jong-Hyock Park; Ji Youl Lee
Journal:  Cancer Res Treat       Date:  2018-02-20       Impact factor: 4.679

  5 in total

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