Literature DB >> 22310568

Comparative outcomes of open nephrectomy, hand-assisted laparoscopic nephrectomy, and full laparoscopic nephrectomy for living donors.

P Ungbhakorn1, W Kongchareonsombat, C Leenanupan, K Kijvikai, W Wisetsingh, S Patcharatrakul, S Jirasiritam.   

Abstract

OBJECTIVE: Kidney transplantation is a standard treatment for end-stage renal disease. There are many methods of harvesting kidneys from living donors. At present, the role of minimally invasive surgery, including hand-assisted and full laparoscopic nephrectomy, is well established and tends to replace open surgery at many institutions. We conducted a retrospective study to compare the outcomes of these operative procedures at Ramathibodi Hospital in Bangkok.
MATERIALS AND METHODS: We retrospectively reviewed 200 patients who underwent open nephrectomy (ON), hand-assisted laparoscopic nephrectomy (HALN), and full laparoscopic nephrectomy (FLN) between January 2006 and November 2010. Demographic data, type of surgical procedure, operative time, warm ischemic time (WIT), length of hospital stay (LOH), estimated blood loss (EBL), analgesic use, and complications from surgery were recorded. Results were compared using a one-way analysis of variance in order to determine differences.
RESULTS: During the study period, 200 living kidney donors underwent nephrectomy. Of these, 95 (47.5%) received ON, 23 (11.5%) received HALN, and 82 (41%) received FLN. The operative time for the patients who underwent HALN and FLN was statistically significantly longer than that of the patients who underwent ON. On the other hand, the EBL for the ON group was significantly greater than for the HALN and FLN groups. The WIT was shortest for the ON group, followed by the HALN and FLN groups. The LOH did not differ among the three groups. Analgesic use was significantly higher in the ON group. Surgical complications were identified in 24 patients (12%).
CONCLUSION: Our results show that laparoscopic living donor nephrectomy is a relatively safe procedure when performed by experienced surgeons at appropriate institutions. Though the operative times and WITs were slightly longer and the cost was higher for the laparoscopic groups, the EBL was lower and the pain score was lower. Indeed, laparoscopic living donor nephrectomy is an attractive alternative surgical procedure. However, there is a long learning curve and experienced surgeons are required.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22310568     DOI: 10.1016/j.transproceed.2011.12.026

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  6 in total

Review 1.  Minimally invasive donor nephrectomy: current state of the art.

Authors:  Nicole M Shockcor; Sam Sultan; Josue Alvarez-Casas; Philip S Brazio; Michael Phelan; John C LaMattina; Rolf N Barth
Journal:  Langenbecks Arch Surg       Date:  2018-08-21       Impact factor: 3.445

Review 2.  Comparison of the laparoscopic versus open live donor nephrectomy: an overview of surgical complications and outcome.

Authors:  H Fonouni; A Mehrabi; M Golriz; M Zeier; B P Müller-Stich; P Schemmer; J Werner
Journal:  Langenbecks Arch Surg       Date:  2014-04-28       Impact factor: 3.445

3.  Back-to-back comparison of mini-open vs. laparoscopic technique for living kidney donation.

Authors:  Christie Rampersad; Premal Patel; Joshua Koulack; Thomas McGregor
Journal:  Can Urol Assoc J       Date:  2016-08       Impact factor: 1.862

Review 4.  A comparison of technique modifications in laparoscopic donor nephrectomy: a systematic review and meta-analysis.

Authors:  Denise M D Özdemir-van Brunschot; Giel G Koning; Kees C J H M van Laarhoven; Mehmet Ergün; Sharon B C E van Horne; Maroeska M Rovers; Michiel C Warlé
Journal:  PLoS One       Date:  2015-03-27       Impact factor: 3.240

Review 5.  Laparoscopic Nephrectomy versus Open Nephrectomy for Patients with Autosomal Dominant Polycystic Kidney Disease: A Systematic Review and Meta-Analysis.

Authors:  Pengyu Guo; Wanhai Xu; Huibo Li; Tong Ren; Shaobin Ni; Minghua Ren
Journal:  PLoS One       Date:  2015-06-08       Impact factor: 3.240

Review 6.  Laparoscopic and hand-assisted laparoscopic donor nephrectomy: A systematic review and meta-analysis.

Authors:  Mark P Broe; Rose Galvin; Lorna G Keenan; Richard E Power
Journal:  Arab J Urol       Date:  2018-07-07
  6 in total

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