Literature DB >> 22310031

A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes.

Pablo Bilbao-Ramos1, Sergio Sifontes-Rodríguez, María Auxiliadora Dea-Ayuela, Francisco Bolás-Fernández.   

Abstract

In this work a simple and novel method to evaluate the efficacy of compounds on intracellular Leishmania amastigotes by using a fluorometric assay has been developed. The new method is sensitive, easy to perform and scalable for high throughput and therefore it could be validated for screening of new anti-leishmanial agents. Copyright Â
© 2012 Elsevier B.V. All rights reserved.

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Year:  2012        PMID： 22310031     DOI： 10.1016/j.mimet.2012.01.013

Source DB:  PubMed          Journal:  J Microbiol Methods        ISSN： 0167-7012            Impact factor:   2.363


  8 in total

Review 1.  Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi.

Authors:  Cristina Fonseca-Berzal; Vicente J Arán; José A Escario; Alicia Gómez-Barrio
Journal:  Parasitol Res       Date:  2018-09-19       Impact factor: 2.289

2.  Systematic search for benzimidazole compounds and derivatives with antileishmanial effects.

Authors:  Juan Carlos Sánchez-Salgado; Pablo Bilbao-Ramos; María Auxiliadora Dea-Ayuela; Francisco Hernández-Luis; Francisco Bolás-Fernández; José L Medina-Franco; Yareli Rojas-Aguirre
Journal:  Mol Divers       Date:  2018-05-10       Impact factor: 2.943

3.  In vitro Screening of Antileishmanial Activity of Natural Product Compounds: Determination of IC50, CC50 and SI Values.

Authors:  Olga S Koutsoni; Kalliopi Karampetsou; Eleni Dotsika
Journal:  Bio Protoc       Date:  2019-11-05

4.  Synthetic oxoisoaporphine alkaloids: in vitro, in vivo and in silico assessment of antileishmanial activities.

Authors:  Eduardo Sobarzo-Sánchez; Pablo Bilbao-Ramos; Maria Dea-Ayuela; Humberto González-Díaz; Matilde Yañez; Eugenio Uriarte; Lourdes Santana; Victoria Martínez-Sernández; Francisco Bolás-Fernández; Florencio M Ubeira
Journal:  PLoS One       Date:  2013-10-29       Impact factor: 3.240

5.  Leishmania mexicana Trypanothione Reductase Inhibitors: Computational and Biological Studies.

Authors:  Félix Matadamas-Martínez; Alicia Hernández-Campos; Alfredo Téllez-Valencia; Alejandra Vázquez-Raygoza; Sandra Comparán-Alarcón; Lilián Yépez-Mulia; Rafael Castillo
Journal:  Molecules       Date:  2019-09-04       Impact factor: 4.411

6.  Past and future of trypanosomatids high-throughput phenotypic screening.

Authors:  Rafael Ferreira Dantas; Eduardo Caio Torres-Santos; Floriano Paes Silva
Journal:  Mem Inst Oswaldo Cruz       Date:  2022-03-11       Impact factor: 2.743

7.  Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.

Authors:  Estefania Calvo-Álvarez; Nestor Adrian Guerrero; Raquel Alvarez-Velilla; Christopher Fernández Prada; Jose María Requena; Carmen Punzón; Miguel Ángel Llamas; Francisco J Arévalo; Luis Rivas; Manuel Fresno; Yolanda Pérez-Pertejo; Rafael Balaña-Fouce; Rosa M Reguera
Journal:  PLoS Negl Trop Dis       Date:  2012-11-29

8.  Nucleotides and AHCC Enhance Th1 Responses In Vitro in Leishmania-Stimulated/Infected Murine Cells.

Authors:  María Auxiliadora Dea-Ayuela; Sergi Segarra; Dolores R Serrano; Francisco Bolás-Fernández
Journal:  Molecules       Date:  2020-08-27       Impact factor: 4.411
  8 in total

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