AIMS: Low serum 25-hydroxyvitamin D (25(OH)D) levels have been linked to metabolic syndrome. However, community-based data for healthy Korean individuals are lacking. We aimed to assess the vitamin D status and the association of 25(OH)D deficiency with metabolic syndrome in the South Korean population (latitude 33-38°N). METHODS: In this population-based study, we assessed 5559 South Korean adults selected from the Korean National Health and Nutrition Examination Survey IV-2, 2008. We used multiple logistic regression analysis to assess the association between vitamin D deficiency and metabolic syndrome. RESULTS: The prevalence of vitamin D deficiency (<20 ng/mL) was 56.0%. Subjects with vitamin D deficiency were younger and had higher education, lower physical activity, and lower alcohol consumption than those with normal vitamin D levels. The overall risk of metabolic syndrome was not associated with 25(OH)D concentration. The adjusted OR of reduced high density lipoprotein cholesterol (HDL-C) decreased across the quintiles of 25(OH)D concentrations (OR=0.72; 95% confidence interval=0.54-0.95 for comparisons of lowest vs. highest quintile; P for trend=0.003). CONCLUSIONS: A high prevalence of vitamin D deficiency was noted in the general South Korean population. Serum 25(OH)D concentration was inversely associated with the risk of having reduced HDL-C.
AIMS: Low serum 25-hydroxyvitamin D (25(OH)D) levels have been linked to metabolic syndrome. However, community-based data for healthy Korean individuals are lacking. We aimed to assess the vitamin D status and the association of 25(OH)D deficiency with metabolic syndrome in the South Korean population (latitude 33-38°N). METHODS: In this population-based study, we assessed 5559 South Korean adults selected from the Korean National Health and Nutrition Examination Survey IV-2, 2008. We used multiple logistic regression analysis to assess the association between vitamin D deficiency and metabolic syndrome. RESULTS: The prevalence of vitamin D deficiency (<20 ng/mL) was 56.0%. Subjects with vitamin D deficiency were younger and had higher education, lower physical activity, and lower alcohol consumption than those with normal vitamin D levels. The overall risk of metabolic syndrome was not associated with 25(OH)D concentration. The adjusted OR of reduced high density lipoprotein cholesterol (HDL-C) decreased across the quintiles of 25(OH)D concentrations (OR=0.72; 95% confidence interval=0.54-0.95 for comparisons of lowest vs. highest quintile; P for trend=0.003). CONCLUSIONS: A high prevalence of vitamin D deficiency was noted in the general South Korean population. Serum 25(OH)D concentration was inversely associated with the risk of having reduced HDL-C.
Authors: Jennifer W Bea; Peter W Jurutka; Elizabeth A Hibler; Peter Lance; Maria E Martínez; Denise J Roe; Christine L Sardo Molmenti; Patricia A Thompson; Elizabeth T Jacobs Journal: Metabolism Date: 2014-11-29 Impact factor: 8.694
Authors: Seung Joo Chon; Bo Hyon Yun; Yeon Soo Jung; Si Hyun Cho; Young Sik Choi; Suk Young Kim; Byung Seok Lee; Seok Kyo Seo Journal: PLoS One Date: 2014-02-21 Impact factor: 3.240