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Literature DB >> 22308478

Hallucinogen actions on human brain revealed.

Hyeong-Min Lee¹, Bryan L Roth.

Abstract

Entities: Disease Species

Mesh：

Substances：
Hallucinogens
Psilocybin

Year: 2012 PMID： 22308478 PMCID： PMC3277578 DOI： 10.1073/pnas.1121358109

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

× No keyword cloud information.

14 in total

1. Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

Authors: G K Aghajanian; G J Marek
Journal: Neuropharmacology Date: 1997 Apr-May Impact factor: 5.250

2. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.

Authors: Javier González-Maeso; Noelia V Weisstaub; Mingming Zhou; Pokman Chan; Lidija Ivic; Rosalind Ang; Alena Lira; Maria Bradley-Moore; Yongchao Ge; Qiang Zhou; Stuart C Sealfon; Jay A Gingrich
Journal: Neuron Date: 2007-02-01 Impact factor: 17.173

3. Mechanism of the 5-hydroxytryptamine 2A receptor-mediated facilitation of synaptic activity in prefrontal cortex.

Authors: Jean-Claude Béïque; Mays Imad; Ljiljana Mladenovic; Jay A Gingrich; Rodrigo Andrade
Journal: Proc Natl Acad Sci U S A Date: 2007-05-29 Impact factor: 11.205

4. Serotonin modulates fast-spiking interneuron and synchronous activity in the rat prefrontal cortex through 5-HT1A and 5-HT2A receptors.

Authors: M Victoria Puig; Akiya Watakabe; Mika Ushimaru; Tetsuo Yamamori; Yasuo Kawaguchi
Journal: J Neurosci Date: 2010-02-10 Impact factor: 6.167

5. 5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites.

Authors: R L Jakab; P S Goldman-Rakic
Journal: Proc Natl Acad Sci U S A Date: 1998-01-20 Impact factor: 11.205

6. Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents.

Authors: R A Glennon; M Titeler; J D McKenney
Journal: Life Sci Date: 1984-12-17 Impact factor: 5.037

7. Quantitative analysis of glutamatergic and GABAergic neurons expressing 5-HT(2A) receptors in human and monkey prefrontal cortex.

Authors: J de Almeida; G Mengod
Journal: J Neurochem Date: 2007-07-17 Impact factor: 5.372

8. Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.

Authors: Bryan L Roth; Karen Baner; Richard Westkaemper; Daniel Siebert; Kenner C Rice; SeAnna Steinberg; Paul Ernsberger; Richard B Rothman
Journal: Proc Natl Acad Sci U S A Date: 2002-08-21 Impact factor: 11.205

9. Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.

Authors: Robin L Carhart-Harris; David Erritzoe; Tim Williams; James M Stone; Laurence J Reed; Alessandro Colasanti; Robin J Tyacke; Robert Leech; Andrea L Malizia; Kevin Murphy; Peter Hobden; John Evans; Amanda Feilding; Richard G Wise; David J Nutt
Journal: Proc Natl Acad Sci U S A Date: 2012-01-23 Impact factor: 11.205

10. Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice.

Authors: Elaine T Weber; Rodrigo Andrade
Journal: Front Neurosci Date: 2010-08-13 Impact factor: 4.677

8 in total

Review 1. Molecular Mechanisms of Psilocybin and Implications for the Treatment of Depression.

Authors: Susan Ling; Felicia Ceban; Leanna M W Lui; Yena Lee; Kayla M Teopiz; Nelson B Rodrigues; Orly Lipsitz; Hartej Gill; Mehala Subramaniapillai; Rodrigo B Mansur; Kangguang Lin; Roger Ho; Joshua D Rosenblat; David Castle; Roger S McIntyre
Journal: CNS Drugs Date: 2021-11-17 Impact factor: 5.749

Review 2. Single treatments that have lasting effects: some thoughts on the antidepressant effects of ketamine and botulinum toxin and the anxiolytic effect of psilocybin.

Authors: Simon N Young
Journal: J Psychiatry Neurosci Date: 2013-03 Impact factor: 6.186

Hallucinogen actions on human brain revealed.

1. Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

2. Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior.

3. Mechanism of the 5-hydroxytryptamine 2A receptor-mediated facilitation of synaptic activity in prefrontal cortex.

4. Serotonin modulates fast-spiking interneuron and synchronous activity in the rat prefrontal cortex through 5-HT1A and 5-HT2A receptors.

5. 5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites.

6. Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents.

7. Quantitative analysis of glutamatergic and GABAergic neurons expressing 5-HT(2A) receptors in human and monkey prefrontal cortex.

8. Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist.

9. Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin.

10. Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice.

Review 1. Molecular Mechanisms of Psilocybin and Implications for the Treatment of Depression.

Review 2. Single treatments that have lasting effects: some thoughts on the antidepressant effects of ketamine and botulinum toxin and the anxiolytic effect of psilocybin.

3. DARK Classics in Chemical Neuroscience: NBOMes.

4. Serotonergic hyperactivity as a potential factor in developmental, acquired and drug-induced synesthesia.

Review 5. Molecular and Functional Imaging Studies of Psychedelic Drug Action in Animals and Humans.

6. Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT_2A Receptor Agonists.

7. Traditional medicines and globalization: current and future perspectives in ethnopharmacology.

8. What Can Neuroscience Tell Us about the Hard Problem of Consciousness?