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Literature DB >> 22308474

H5N1 influenza viruses: facts, not fear.

Abstract

The ongoing controversy over publication of two studies involving the transmission in ferrets of H5N1 (H5) subtype influenza viruses and the recommendations of the National Science Advisory Board for Biosecurity to redact key details in the manuscripts call for an examination of relevant scientific facts. In addition, there are calls in the media to destroy the viruses, curtail future research in this area, and protect the public from such "frightening" research efforts. Fear needs to be put to rest with solid science and not speculation.

Entities: Species

Mesh：

Year: 2012 PMID： 22308474 PMCID： PMC3289294 DOI： 10.1073/pnas.1121297109

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

47 in total

1. Risk of influenza A (H5N1) infection among poultry workers, Hong Kong, 1997-1998.

Authors: Carolyn Buxton Bridges; Wilina Lim; Jean Hu-Primmer; Les Sims; Keiji Fukuda; K H Mak; Thomas Rowe; William W Thompson; Laura Conn; Xiuhua Lu; Nancy J Cox; Jacqueline M Katz
Journal: J Infect Dis Date: 2002-03-19 Impact factor: 5.226

2. Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model.

Authors: J Brian Kimble; Erin Sorrell; Hongxia Shao; Philip L Martin; Daniel Roberto Perez
Journal: Proc Natl Acad Sci U S A Date: 2011-07-05 Impact factor: 11.205

Review 3. New strategies for the development of H5N1 subtype influenza vaccines: progress and challenges.

Authors: John Steel
Journal: BioDrugs Date: 2011-10-01 Impact factor: 5.807

4. In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity.

Authors: Li-Mei Chen; Ola Blixt; James Stevens; Aleksandr S Lipatov; Charles T Davis; Brian E Collins; Nancy J Cox; James C Paulson; Ruben O Donis
Journal: Virology Date: 2011-11-05 Impact factor: 3.616

5. Emergent 2009 influenza A(H1N1) viruses containing HA D222N mutation associated with severe clinical outcomes in the Americas.

Authors: Huo-Shu H Houng; Jason Garner; Yanfei Zhou; Arthur Lyons; Robert Kuschner; Gregory Deye; Kristina St Clair; Richard W Douce; Wilson Chicaiza; Patrick J Blair; Christopher A Myers; Ronald L Burke; Jose L Sanchez; Maya Williams; Eric S Halsey
Journal: J Clin Virol Date: 2011-10-28 Impact factor: 3.168

6. Pathogenesis and transmission of triple-reassortant swine H1N1 influenza viruses isolated before the 2009 H1N1 pandemic.

Authors: Jessica A Belser; Kortney M Gustin; Taronna R Maines; Dianna M Blau; Sherif R Zaki; Jacqueline M Katz; Terrence M Tumpey
Journal: J Virol Date: 2010-12-01 Impact factor: 5.103

7. Evidence for subclinical avian influenza virus infections among rural Thai villagers.

Authors: Benjawan P Khuntirat; In-Kyu Yoon; Patrick J Blair; Whitney S Krueger; Malinee Chittaganpitch; Shannon D Putnam; Krongkaew Supawat; Robert V Gibbons; Sirima Pattamadilok; Pathom Sawanpanyalert; Gary L Heil; John A Friary; Ana W Capuano; Gregory C Gray
Journal: Clin Infect Dis Date: 2011-10 Impact factor: 9.079

8. Comparative pathology in ferrets infected with H1N1 influenza A viruses isolated from different hosts.

Authors: Jennifer Humberd Smith; Tamas Nagy; Elizabeth Driskell; Paula Brooks; S Mark Tompkins; Ralph A Tripp
Journal: J Virol Date: 2011-05-18 Impact factor: 5.103

9. Pathogenesis of avian influenza A (H5N1) viruses in ferrets.

Authors: Lois A Zitzow; Thomas Rowe; Timothy Morken; Wun-Ju Shieh; Sherif Zaki; Jacqueline M Katz
Journal: J Virol Date: 2002-05 Impact factor: 5.103

10. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus.

Authors: Rafael A Medina; Balaji Manicassamy; Silke Stertz; Christopher W Seibert; Rong Hai; Robert B Belshe; Sharon E Frey; Christopher F Basler; Peter Palese; Adolfo García-Sastre
Journal: Nat Commun Date: 2010-06-15 Impact factor: 14.919

34 in total

1. Ferretting out the facts behind the H5N1 controversy.

Authors: Roy D Sleator
Journal: Bioeng Bugs Date: 2012-05-01

2. Death-rate row blurs mutant flu debate.

Authors: Declan Butler
Journal: Nature Date: 2012-02-13 Impact factor: 49.962

3. H5N1 influenza virus seroepidemiological studies: the facts revisited.

Authors: Michael T Osterholm; Nicholas S Kelley
Journal: Proc Natl Acad Sci U S A Date: 2012-05-01 Impact factor: 11.205

Review 4. H5N1 vaccines in humans.

Authors: Mariana Baz; Catherine J Luke; Xing Cheng; Hong Jin; Kanta Subbarao
Journal: Virus Res Date: 2013-05-28 Impact factor: 3.303

5. An inactivated, adjuvanted whole virion clade 2.2 H5N1 (A/Chicken/Astana/6/05) influenza vaccine is safe and immunogenic in a single dose in humans.

Authors: Abylay R Sansyzbay; Marianna K Erofeeva; Berik M Khairullin; Nurlan T Sandybayev; Zhailaubay K Kydyrbayev; Seidigapbar M Mamadaliyev; Markhabat M Kassenov; Maria V Sergeeva; Julia R Romanova; Vera Z Krivitskaya; Oleg I Kiselev; Marina A Stukova
Journal: Clin Vaccine Immunol Date: 2013-06-26

6. From cases to capacity? A critical reflection on the role of 'ethical dilemmas' in the development of dual-use governance.

Authors: Brett Edwards; James Revill; Louise Bezuidenhout
Journal: Sci Eng Ethics Date: 2013-05-24 Impact factor: 3.525

Review 7. A cross-species view on viruses.

Authors: Sara L Sawyer; Nels C Elde
Journal: Curr Opin Virol Date: 2012-07-24 Impact factor: 7.090