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Literature DB >> 22307409

Genetic variation in the epigenetic machinery and mental health.

Abstract

DNA methylation and chromatin modifications regulate gene expression and contribute to changes in brain transcriptomes underlying neurodevelopmental and psychiatric disorders. Clinical genetics and preclinical animal models highlight the crucial importance of the correct establishment of epigenetic marks during sensitive windows of development for normal brain function. On the same side of the coin, some of the concerned factors also appear engaged in the programming of experience-dependent long-term effects on mental health following exposure to relevant early-life events. Delineating the particular role of genetic variations in these players could provide new insights into the molecular basis of vulnerability and resilience and advance tailored therapies.

Entities: Disease

Mesh：

Substances：

Year: 2012 PMID： 22307409 DOI： 10.1007/s11920-012-0255-1

Source DB: PubMed Journal: Curr Psychiatry Rep ISSN： 1523-3812 Impact factor: 5.285

99 in total

1. Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.

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Journal: Genes Dev Date: 2001-03-15 Impact factor: 11.361

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Journal: Hum Mutat Date: 2008-06 Impact factor: 4.878

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Authors: Nils Rademacher; Melanie Hambrock; Ute Fischer; Bettina Moser; Berten Ceulemans; Wolfgang Lieb; Rainer Boor; Irina Stefanova; Gabriele Gillessen-Kaesbach; Charlotte Runge; Georg Christoph Korenke; Stefanie Spranger; Franco Laccone; Andreas Tzschach; Vera M Kalscheuer
Journal: Neurogenetics Date: 2011-02-12 Impact factor: 2.660

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Authors: Shusaku Uchida; Kumiko Hara; Ayumi Kobayashi; Koji Otsuki; Hirotaka Yamagata; Teruyuki Hobara; Takayoshi Suzuki; Naoki Miyata; Yoshifumi Watanabe
Journal: Neuron Date: 2011-01-27 Impact factor: 17.173

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Authors: Zhifeng Zhou; Qiaoping Yuan; Deborah C Mash; David Goldman
Journal: Proc Natl Acad Sci U S A Date: 2011-04-04 Impact factor: 11.205

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Authors: João D Pereira; Stephen N Sansom; James Smith; Marc-Werner Dobenecker; Alexander Tarakhovsky; Frederick J Livesey
Journal: Proc Natl Acad Sci U S A Date: 2010-08-23 Impact factor: 11.205

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Authors: Robert A Philibert
Journal: Psychiatr Genet Date: 2006-04 Impact factor: 2.458

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Authors: Edward Korzus; Michael G Rosenfeld; Mark Mayford
Journal: Neuron Date: 2004-06-24 Impact factor: 17.173

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Authors: Charles E Schwartz; Patrick S Tarpey; Herbert A Lubs; Alain Verloes; Melanie M May; Hiba Risheg; Michael J Friez; P Andrew Futreal; Sarah Edkins; Jon Teague; Sylvain Briault; Cindy Skinner; Astrid Bauer-Carlin; Richard J Simensen; Sumy M Joseph; Julie R Jones; Josef Gecz; Michael R Stratton; F Lucy Raymond; Roger E Stevenson
Journal: J Med Genet Date: 2007-03-16 Impact factor: 6.318

10. GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes.

Authors: Michael O Poulter; Lisheng Du; Ian C G Weaver; Miklós Palkovits; Gábor Faludi; Zul Merali; Moshe Szyf; Hymie Anisman
Journal: Biol Psychiatry Date: 2008-07-18 Impact factor: 13.382

18 in total

Review 1. Transcriptional co-repressors and memory storage.

Authors: Hannah Schoch; Ted Abel
Journal: Neuropharmacology Date: 2014-01-17 Impact factor: 5.250

2. Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers.

Authors: Hyuna Sung; Howard H Yang; Han Zhang; Qi Yang; Nan Hu; Ze-Zhong Tang; Hua Su; Lemin Wang; Chaoyu Wang; Ti Ding; Jin-Hu Fan; You-Lin Qiao; William Wheeler; Carol Giffen; Laurie Burdett; Zhaoming Wang; Maxwell P Lee; Stephen J Chanock; Sanford M Dawsey; Neal D Freedman; Christian C Abnet; Alisa M Goldstein; Kai Yu; Philip R Taylor; Paula L Hyland
Journal: Int J Epidemiol Date: 2015-04-27 Impact factor: 7.196

Review 3. The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome.

Authors: Nikolaos P Daskalakis; Rosemary C Bagot; Karen J Parker; Christiaan H Vinkers; E R de Kloet
Journal: Psychoneuroendocrinology Date: 2013-07-07 Impact factor: 4.905

4. Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk.

Authors: Chiara Grasso; Maja Popovic; Elena Isaevska; Fulvio Lazzarato; Valentina Fiano; Daniela Zugna; John Pluta; Benita Weathers; Kurt D'Andrea; Kristian Almstrup; Lynn Anson-Cartwright; D Timothy Bishop; Stephen J Chanock; Chu Chen; Victoria K Cortessis; Marlene D Dalgaard; Siamak Daneshmand; Alberto Ferlin; Carlo Foresta; Megan N Frone; Marija Gamulin; Jourik A Gietema; Mark H Greene; Tom Grotmol; Robert J Hamilton; Trine B Haugen; Russ Hauser; Robert Karlsson; Lambertus A Kiemeney; Davor Lessel; Patrizia Lista; Ragnhild A Lothe; Chey Loveday; Coby Meijer; Kevin T Nead; Jérémie Nsengimana; Rolf I Skotheim; Clare Turnbull; David J Vaughn; Fredrik Wiklund; Tongzhang Zheng; Andrea Zitella; Stephen M Schwartz; Katherine A McGlynn; Peter A Kanetsky; Katherine L Nathanson; Lorenzo Richiardi
Journal: Cancer Epidemiol Biomarkers Prev Date: 2022-09-02 Impact factor: 4.090