Literature DB >> 22306772

[Synthetic calcium phosphate ceramics in secondary alveoloplasty].

P Corre1, R-H Khonsari, B Laure, K Elamrani, P Weiss, J-M Mercier.   

Abstract

INTRODUCTION: Bone substitutes are rarely used in the reconstruction of cleft lip and palate. The graft material of choice is cancellous bone, harvested in the hip or tibia. Tibial harvesting may lead to postoperative morbidity, or even complications. This has lead surgeons to develop alternative solution. We present a secondary alveolar bone grafting technique using synthetic calcium phosphate ceramics. OBSERVATION: A patient presenting with a complete unilateral cleft lip and palate was treated by alveolar bone grafting at the age of nine years, using a mixture of autologous bone, harvested on the operative field, and particles of biphasic calcium phosphate (BCP); the graft was included in a platelet rich plasma (PRP) gel. The patient was followed up for eight years after the procedure. No sign of early or late infection was observed. At the end of facial growth, the cuspid had erupted correctly in a safe periodontal environment. Sequential X-rays showed complete filling of the initial bone defect, progressive resorption of ceramics, and spontaneous eruption of the cuspid. DISCUSSION: In this long-term follow-up report, the use of BCP mixed with autologous bone did not interfere with dental eruption or maxilla growth. A second bone-harvesting site was thus avoided. BCP could be a suitable alternative to autologous bone graft for secondary alveoloplasty.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.

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Year:  2012        PMID: 22306772     DOI: 10.1016/j.stomax.2011.12.012

Source DB:  PubMed          Journal:  Rev Stomatol Chir Maxillofac        ISSN: 0035-1768


  2 in total

1.  Alveolar bone graft with Platelet Rich Plasma in cleft alveolus.

Authors:  Chandan Gupta; Divya Mehrotra; Shadab Mohammad; Vaibhav Khanna; Gulshan Kumar Singh; Geeta Singh; Arul A L Chellappa; Deepak Passi
Journal:  J Oral Biol Craniofac Res       Date:  2013-02-24

2.  Determining a clinically relevant strategy for bone tissue engineering: an "all-in-one" study in nude mice.

Authors:  Pierre Corre; Christophe Merceron; Caroline Vignes; Sophie Sourice; Martial Masson; Nicolas Durand; Florent Espitalier; Paul Pilet; Thomas Cordonnier; Jacques Mercier; Séverine Remy; Ignacio Anegon; Pierre Weiss; Jérôme Guicheux
Journal:  PLoS One       Date:  2013-12-11       Impact factor: 3.240

  2 in total

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