Literature DB >> 22306214

Extending the scope of mitral valve repair in active endocarditis.

Laurent de Kerchove1, Joel Price, Saadallah Tamer, David Glineur, Mona Momeni, Philippe Noirhomme, Gebrine ElKhoury.   

Abstract

OBJECTIVE: During the last 2 decades, we have applied a repair-oriented surgical approach to patients with active mitral valve endocarditis. We retrospectively analyzed the long-term outcomes with this repair-oriented approach.
METHOD: Between 1991 and 2010, 137 patients underwent operation for active mitral valve endocarditis; of these, 109 patients (80%) had mitral valve repair and represent the study cohort. Repair techniques without patch extension (no-patch techniques) include triangular or quadrangular resection (n = 49), sliding plasty (n = 24), neochordae (n = 18), chordal transfer (n = 12), and others (n = 5). Repair techniques using patch extension (patch techniques) included pericardium (n = 42), tricuspid autograft (n = 8), flip-over technique (n = 7), and partial mitral valve homograft (n = 5). Patches were used in 67 patients (61%). Ring annuloplasty was performed in 60 patients, and a pericardial band was used in 13 patients. Clinical and echocardiographic follow-up were performed. Median follow-up was 48 months.
RESULTS: Hospital mortality was 16%. At 8 years, overall survival was 62% ± 10% with no differences between patients with or without patch repair (P = .5). Freedom from mitral valve repair failure was 81% ± 14% in patients with patch repair and 90% ± 10% in patients without patch repair (P = .09). The rate of thromboembolic or bleeding event was 1% per patient-year, and the rate of endocarditis recurrence was 0.3% per patient-year. Univariable predictors of mortality were age more than 70 years (P < .0001), perivalvular abscess (P = .002), diabetes mellitus (P = .0002), and renal failure (P = .04). Predictors of repair failure were renal failure (P = .035) and perivalvular abscess (P = .033).
CONCLUSIONS: In active mitral valve endocarditis, a repair-oriented surgical approach achieves a reparability rate of 80% with acceptable morbidity and good long-term results. The use of patch techniques offers a durability rate that approximates the rate obtained with the no-patch techniques. Copyright Â
© 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID: 22306214     DOI: 10.1016/j.jtcvs.2012.01.049

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  8 in total

1.  Reappraisal of a single-centre policy on the contemporary surgical management of active infective endocarditis.

Authors:  Frank Caes; Thierry Bové; Yves Van Belleghem; Guy Vandenplas; Guido Van Nooten; Katrien François
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-10-30

2.  Reconstruction of anterior mitral leaflet using autologous pericardial patch combined with posterior leaflet sliding for active infective endocarditis.

Authors:  Satoshi Kimura; Yuta Yamaki; Masayoshi Umesue
Journal:  Gen Thorac Cardiovasc Surg       Date:  2013-04-24

Review 3.  Repair of infected mitral valves: what have we learned?

Authors:  Yu-Ning Hu; Song Wan
Journal:  Surg Today       Date:  2018-02-21       Impact factor: 2.549

4.  Reconstruction of mitral valve chordae and leaflets with one piece of autologous pericardium in extensively destructed mitral valve due to active infective endocarditis.

Authors:  Toshiaki Ito; Atsuo Maekawa; Sadanari Sawaki; Genyo Fujii; Satoshi Hoshino; Yasunari Hayashi
Journal:  Gen Thorac Cardiovasc Surg       Date:  2013-01-05

5.  Isolated mitral valve endocarditis: Patient, disease, and surgical factors that influence outcomes.

Authors:  Ryan A Moore; James C Witten; Ashley M Lowry; Nabin K Shrestha; Eugene H Blackstone; Shinya Unai; Gösta B Pettersson; Per Wierup
Journal:  J Thorac Cardiovasc Surg       Date:  2022-04-05       Impact factor: 6.439

6.  Surgical management of mitral valve infective endocarditis with annular abscess and calcification in the setting of a leaking mycotic infrarenal abdominal aortic aneurysm: a case report.

Authors:  Jordan D W Ross; Masashi Ura; Allan Kruger; Jeremy Wright
Journal:  J Cardiothorac Surg       Date:  2014-09-20       Impact factor: 1.637

7.  Role of mitral valve repair in active infective endocarditis: long term results.

Authors:  Carlo Rostagno; Enrico Carone; Pier Luigi Stefàno
Journal:  J Cardiothorac Surg       Date:  2017-05-18       Impact factor: 1.637

8.  Infective endocarditis and neurologic events: indications and timing for surgical interventions.

Authors:  Nikolaos Bonaros; Martin Czerny; Bettina Pfausler; Silvana Müller; Thomas Bartel; Matthias Thielmann; Sharaf-Eldin Shehada; Thierry Folliguet; Jean-Francois Obadia; Johannes Holfeld; Roberto Lorusso; Alessandro Parolari; Ludwig Müller; Michael Grimm; Elfriede Ruttmann-Ulmer
Journal:  Eur Heart J Suppl       Date:  2020-12-06       Impact factor: 1.803

  8 in total

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