Literature DB >> 22306065

Production and characterization of Clostridium perfringens recombinant β toxoid.

Adalgisa Milach1, João Rodrigo Gil de los Santos, Carlos Gil Turnes, Angela Nunes Moreira, Ronnie Antunes de Assis, Felipe Masiero Salvarani, Francisco Carlos Faria Lobato, Fabricio Rochedo Conceição.   

Abstract

In this work, we produced and evaluated a vaccine based on a β toxoid of Clostridium perfringens type C produced in Escherichia coli (rBT). The non-toxic rBT was innocuous for mice and induced 14 IU mL(-1) of β antitoxin in rabbits, complying with the European Pharmacopeia and CFR9 - USDA guidelines.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22306065     DOI： 10.1016/j.anaerobe.2012.01.004

Source DB:  PubMed          Journal:  Anaerobe        ISSN： 1075-9964            Impact factor:   3.331


  7 in total

Review 1.  Recent insights into Clostridium perfringens beta-toxin.

Authors:  Masahiro Nagahama; Sadayuki Ochi; Masataka Oda; Kazuaki Miyamoto; Masaya Takehara; Keiko Kobayashi
Journal:  Toxins (Basel)       Date:  2015-02-03       Impact factor: 4.546

Review 2.  Recombinant Alpha, Beta, and Epsilon Toxins of Clostridium perfringens: Production Strategies and Applications as Veterinary Vaccines.

Authors:  Marcos Roberto A Ferreira; Gustavo Marçal S G Moreira; Carlos Eduardo P da Cunha; Marcelo Mendonça; Felipe M Salvarani; Ângela N Moreira; Fabricio R Conceição
Journal:  Toxins (Basel)       Date:  2016-11-21       Impact factor: 4.546

3.  Targeted Mass Spectrometry Analysis of Clostridium perfringens Toxins.

Authors:  Miloslava Duracova; Jana Klimentova; Alena Myslivcova Fucikova; Lenka Zidkova; Valeria Sheshko; Helena Rehulkova; Jiri Dresler; Zuzana Krocova
Journal:  Toxins (Basel)       Date:  2019-03-23       Impact factor: 4.546

Review 4.  Vaccination against pathogenic clostridia in animals: a review.

Authors:  Lida Abdolmohammadi Khiav; Azadeh Zahmatkesh
Journal:  Trop Anim Health Prod       Date:  2021-04-23       Impact factor: 1.559

5.  Immunogenic and neutralization efficacy of recombinant perfringolysin O of Clostridium perfringens and its C-terminal receptor-binding domain in a murine model.

Authors:  Ankita Singh; Prashant Rawat; Devapriya Choudhury; Aparna Dixit
Journal:  Immunol Res       Date:  2022-01-15       Impact factor: 4.505

6.  Humoral Immune Response Evaluation in Horses Vaccinated with Recombinant Clostridium perfringens Toxoids Alpha and Beta for 12 Months.

Authors:  Nayra F Q R Freitas; Denis Y Otaka; Cleideanny C Galvão; Dayane M de Almeida; Marcos R A Ferreira; Clóvis Moreira Júnior; Marina M M H Hidalgo; Fabricio R Conceição; Felipe M Salvarani
Journal:  Toxins (Basel)       Date:  2021-08-13       Impact factor: 4.546

7.  Immunogenicity of a Trivalent Recombinant Vaccine Against Clostridium perfringens Alpha, Beta, and Epsilon Toxins in Farm Ruminants.

Authors:  Gustavo Marçal Schmidt Garcia Moreira; Felipe Masiero Salvarani; Carlos Eduardo Pouey da Cunha; Marcelo Mendonça; Ângela Nunes Moreira; Luciana Aramuni Gonçalves; Prhiscylla Sadanã Pires; Francisco Carlos Faria Lobato; Fabricio Rochedo Conceição
Journal:  Sci Rep       Date:  2016-03-23       Impact factor: 4.379
  7 in total

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