Literature DB >> 22305560

Engineering stem cell expansion.

Irwin D Bernstein1, Colleen Delaney.   

Abstract

In this issue of Cell Stem Cell, Csaszar et al. (2012) develop a culture method that overcomes current limitations in ex vivo hematopoietic stem/progenitor cell expansion by continuously diluting inhibitory signaling factors and maintaining stem cell density. This approach enhances the generation of precursors with potential therapeutic utility.
Copyright © 2012 Elsevier Inc. All rights reserved.

Mesh：

Year:  2012        PMID： 22305560     DOI： 10.1016/j.stem.2012.01.012

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  5 in total

Review 1.  Concise review: stem cell-based approaches to red blood cell production for transfusion.

Authors:  Siddharth Shah; Xiaosong Huang; Linzhao Cheng
Journal:  Stem Cells Transl Med       Date:  2013-12-20       Impact factor: 6.940

Review 2.  Concise review: ex vivo expansion of cord blood-derived hematopoietic stem and progenitor cells: basic principles, experimental approaches, and impact in regenerative medicine.

Authors:  Patricia Flores-Guzmán; Verónica Fernández-Sánchez; Hector Mayani
Journal:  Stem Cells Transl Med       Date:  2013-10-07       Impact factor: 6.940

3.  Glypican-3-mediated inhibition of CD26 by TFPI: a novel mechanism in hematopoietic stem cell homing and maintenance.

Authors:  Satish Khurana; Lia Margamuljana; Chacko Joseph; Sarah Schouteden; Shannon M Buckley; Catherine M Verfaillie
Journal:  Blood       Date:  2013-01-17       Impact factor: 22.113

4.  PGE2 maintains self-renewal of human adult stem cells via EP2-mediated autocrine signaling and its production is regulated by cell-to-cell contact.

Authors:  Byung-Chul Lee; Hyung-Sik Kim; Tae-Hoon Shin; Insung Kang; Jin Young Lee; Jae-Jun Kim; Hyun Kyoung Kang; Yoojin Seo; Seunghee Lee; Kyung-Rok Yu; Soon Won Choi; Kyung-Sun Kang
Journal:  Sci Rep       Date:  2016-05-27       Impact factor: 4.379

5.  Expansion of human and murine hematopoietic stem and progenitor cells ex vivo without genetic modification using MYC and Bcl-2 fusion proteins.

Authors:  Gregory A Bird; Avital Polsky; Patricia Estes; Teri Hanlon; Haley Hamilton; John J Morton; Jonathan Gutman; Antonio Jimeno; Brian C Turner; Yosef Refaeli
Journal:  PLoS One       Date:  2014-08-29       Impact factor: 3.240
  5 in total

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