Literature DB >> 22303869

A domino approach of Heck coupling for the synthesis of β-trifluoromethylstyrenes.

G K Surya Prakash1, Hema S Krishnan, Parag V Jog, Anjali P Iyer, George A Olah.   

Abstract

A domino approach of Heck coupling was used to synthesize β-trifluoromethylstyrene derivatives from iodoarenes and 1-iodo-3,3,3-trifluoropropane in moderate to good yields. This method avoids the use of low-boiling, gaseous reagents such as 3,3,3-trifluoropropene, and additives and phosphines in the catalytic system.

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Year:  2012        PMID: 22303869     DOI: 10.1021/ol300076y

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

1.  Julia-Kocienski Approach to Trifluoromethyl-Substituted Alkenes1.

Authors:  Deborah O Ayeni; Samir K Mandal; Barbara Zajc
Journal:  Tetrahedron Lett       Date:  2013-11-06       Impact factor: 2.415

2.  Product Control in Alkene Trifluoromethylation: Hydrotrifluoromethylation, Vinylic Trifluoromethylation, and Iodotrifluoromethylation using Togni Reagent.

Authors:  Hiromichi Egami; Yoshihiko Usui; Shintaro Kawamura; Sayoko Nagashima; Mikiko Sodeoka
Journal:  Chem Asian J       Date:  2015-06-16

3.  Oxidative 3,3,3-trifluoropropylation of arylaldehydes.

Authors:  Akari Ikeda; Masaaki Omote; Shiho Nomura; Miyuu Tanaka; Atsushi Tarui; Kazuyuki Sato; Akira Ando
Journal:  Beilstein J Org Chem       Date:  2013-11-11       Impact factor: 2.883

4.  Direct C-H trifluoromethylation of di- and trisubstituted alkenes by photoredox catalysis.

Authors:  Ren Tomita; Yusuke Yasu; Takashi Koike; Munetaka Akita
Journal:  Beilstein J Org Chem       Date:  2014-05-12       Impact factor: 2.883

  4 in total

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