Literature DB >> 22303528

Metabolism of crystals within the joint.

F Oliviero1, A Scanu, L Punzi.   

Abstract

Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.

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Year:  2012        PMID： 22303528     DOI： 10.4081/reumatismo.2011.221

Source DB:  PubMed          Journal:  Reumatismo        ISSN： 0048-7449


  7 in total

1.  Urate crystal degradation for treatment of gout: a nanoparticulate combination therapy approach.

Authors:  Sanjay Tiwari; Harinath Dwivedi; Koshy M Kymonil; Shubhini A Saraf
Journal:  Drug Deliv Transl Res       Date:  2015-06       Impact factor: 4.617

Review 2.  Dysregulation of phosphate metabolism and conditions associated with phosphate toxicity.

Authors:  Ronald B Brown; Mohammed S Razzaque
Journal:  Bonekey Rep       Date:  2015-06-03

Review 3.  Crystal arthritides - gout and calcium pyrophosphate arthritis : Part 1: Epidemiology and pathophysiology.

Authors:  S Schlee; L C Bollheimer; T Bertsch; C C Sieber; P Härle
Journal:  Z Gerontol Geriatr       Date:  2017-02-23       Impact factor: 1.281

4.  Integrated Molecular Docking with Network Pharmacology to Reveal the Molecular Mechanism of Simiao Powder in the Treatment of Acute Gouty Arthritis.

Authors:  Yihua Fan; Wei Liu; Yue Jin; Xu Hou; Xuewu Zhang; Hudan Pan; Hang Lu; Xiaojing Guo
Journal:  Evid Based Complement Alternat Med       Date:  2021-04-27       Impact factor: 2.629

Review 5.  Inflammatory Response to Regulated Cell Death in Gout and Its Functional Implications.

Authors:  Jianan Zhao; Kai Wei; Ping Jiang; Cen Chang; Lingxia Xu; Linshuai Xu; Yiming Shi; Shicheng Guo; Yu Xue; Dongyi He
Journal:  Front Immunol       Date:  2022-04-06       Impact factor: 8.786

Review 6.  Factors influencing the crystallization of monosodium urate: a systematic literature review.

Authors:  Ashika Chhana; Gerald Lee; Nicola Dalbeth
Journal:  BMC Musculoskelet Disord       Date:  2015-10-14       Impact factor: 2.362

7.  Monosodium Urate Crystal-Induced Chondrocyte Death via Autophagic Process.

Authors:  Hyun Sook Hwang; Chung Mi Yang; Su Jin Park; Hyun Ah Kim
Journal:  Int J Mol Sci       Date:  2015-12-08       Impact factor: 5.923
  7 in total

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